Mechanism insights of curcumin and its analogues in cancer: An update

P Joshi, K Verma, D Kumar Semwal… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Curcuma Longa: Nutraceutical Use and Association With Nanotechnology

G Corrêa Carvalho, GD Marena… - Advanced …, 2024 - Wiley Online Library
Curcumin is a natural product found in the rhizome of Curcuma longa (L.) and other
Curcuma spp. As a lipophilic molecule, it has greater affinity for polar, non‐polar, alkaline, or …

Therapeutic effects of curcumin derivatives against obesity and associated metabolic complications: a review of in vitro and in vivo studies

MT Moetlediwa, R Ramashia, C Pheiffer… - International Journal of …, 2023 - mdpi.com
Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic
diseases. Thus, the need to identify more effective anti-obesity agents has spurred …

[HTML][HTML] Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan

S Idoudi, T Bedhiafi, F Sahir, Y Hijji, S Uddin… - International Journal of …, 2023 - Elsevier
Colon cancer (CRC) is the second leading cause of death and the third most diagnosed
cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity …

Applications of curcumin and its nanoforms in the treatment of cancer

D Mundekkad, WC Cho - Pharmaceutics, 2023 - mdpi.com
Due to the diverse medicinal and pharmacokinetic properties of turmeric, it is well-known in
the therapeutic, pharmaceutic, nutraceutical, cosmetic, and dietary industries. It gained …

Role of Nrf2, STAT3, and Src as molecular targets for cancer chemoprevention

H Ahsan, SU Islam, MB Ahmed, YS Lee - Pharmaceutics, 2022 - mdpi.com
Cancer is a complex and multistage disease that affects various intracellular pathways,
leading to rapid cell proliferation, angiogenesis, cell motility, and migration, supported by …

Improved solubility and activity of natural product in nanohydrogel

U Lestari, M Muhaimin, AY Chaerunisaa, W Sujarwo - Pharmaceuticals, 2023 - mdpi.com
With the development of technology, natural material components are widely used in various
fields of science. Natural product components in phytochemical compounds are secondary …

[HTML][HTML] Anti-Cancer Properties of Two Intravenously Administrable Curcumin Formulations as Evaluated in the 3D Patient-Derived Cancer Spheroid Model

M Niederreiter, J Klein, SBM Schmitz, J Werner… - International journal of …, 2024 - mdpi.com
Curcumin (Cur) is a heavily used complementary derived drug from cancer patients.
Spheroid samples derived from 82 patients were prepared and treated after 48 h with two …

Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel

S Qin, Q Su, X Li, M Shao, Y Zhang, F Yu, Y Ni… - Lipids in Health and …, 2023 - Springer
Abstract Background Curcumin (Cur) is a bioactive dietary polyphenol of turmeric with
various biological activities against several cancers. Colorectal cancer (CRC) is one of the …

Amplifying Curcumin's Antitumor Potential: A Heat-Driven Approach for Colorectal Cancer Treatment

J Kabagwira, RN Fuller, PA Vallejos… - OncoTargets and …, 2024 - Taylor & Francis
Introduction Peritoneal metastases from colorectal cancer (CRC) present a significant
clinical challenge with poor prognosis, often unresponsive to systemic chemotherapy …