Noise-induced hearing loss (NIHL) is the second most common cause of sensorineural
hearing loss, after age-related hearing loss, and affects approximately 5% of the world's …

The classic view of sensorineural hearing loss has been that the primary damage targets are
hair cells and that auditory nerve loss is typically secondary to hair cell degeneration …

The classic view of sensorineural hearing loss (SNHL) is that the “primary” targets are hair
cells, and that cochlear-nerve loss is “secondary” to hair cell degeneration. Our recent work …

Aging listeners experience greater difficulty understanding speech in adverse listening
conditions and exhibit degraded temporal resolution, even when audiometric thresholds are …

Recent animal work has suggested that cochlear synapses are more vulnerable than hair
cells in both noise-induced and age-related hearing loss. This synaptopathy is invisible in …

Overexposure to intense sound can cause temporary or permanent hearing loss.
Postexposure recovery of threshold sensitivity has been assumed to indicate reversal of …

Sensorineural hearing impairment is the most common form of hearing loss, and
encompasses pathologies of the cochlea and the auditory nerve. Hearing impairment …

Cochlear synaptic loss, rather than hair cell death, is the earliest sign of damage in both
noise-and age-related hearing impairment (;). Here, we compare cochlear aging after two …

In recent years, sensory neuroscientists have made major efforts to dissect the structure and
function of ribbon synapses which process sensory information in the eye and ear. This …

Hearing loss due to damage to auditory hair cells is normally irreversible because
mammalian hair cells do not regenerate. Here, we show that new hair cells can be induced …