Mechanistic inhibition of gastric cancer-associated bacteria Helicobacter pylori by selected phytocompounds: A new cutting-edge computational approach
Background Helicobacter pylori (H. pylori) is a persistent bacterial inhabitant in the stomachs
of approximately half the global populace. This bacterium is directly linked to chronic …
of approximately half the global populace. This bacterium is directly linked to chronic …
Anti-viral drug discovery against monkeypox and smallpox infection by natural curcumin derivatives: A Computational drug design approach
Background In the last couple of years, viral infections have been leading the globe,
considered one of the most widespread and extremely damaging health problems and one …
considered one of the most widespread and extremely damaging health problems and one …
Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses
Antibiotics are the drugs that are used for the management of microbial diseases. However,
these conventional synthetic drugs can harmfully affect the human health. Since …
these conventional synthetic drugs can harmfully affect the human health. Since …
New quinoxaline-oxadiazole hybrids as tubulin inhibitors: Synthesis, cytotoxicity, and molecular dynamics simulations
BR Vancha, M Sreeshitha, KP Vasikarla… - Journal of Molecular …, 2025 - Elsevier
This study describes the synthesis and biological evaluation of a series of novel quinoxaline-
oxadiazole hybrid compounds. These compounds were designed to enhance anticancer …
oxadiazole hybrid compounds. These compounds were designed to enhance anticancer …
Bioinformatic investigation of Nipah virus surface protein mutations: Molecular docking with Ephrin B2 receptor, molecular dynamics simulation, and structural impact …
E Aktaş, İ Saygılı, E Kahveci, Z Tekbıyık… - Microbiology and …, 2023 - Wiley Online Library
The SARS‐CoV‐2 outbreak resulted in significant challenges and loss of life. The Nipah
virus, known for its high infectivity and severity, was designated an emergency concern by …
virus, known for its high infectivity and severity, was designated an emergency concern by …
Identification of significant hub genes and pathways associated with metastatic breast cancer and tolerogenic dendritic cell via bioinformatics analysis
Metastatic breast cancer (MBC) is an advanced-stage breast cancer associated with more
than 90% of cancer-related deaths. Immunosuppressive properties of tolerogenic dendritic …
than 90% of cancer-related deaths. Immunosuppressive properties of tolerogenic dendritic …
An Integrated Approach to Develop a Potent Vaccine Candidate Construct Against Prostate Cancer by Utilizing Machine Learning and Bioinformatics
A Albutti - Cancer Reports, 2024 - Wiley Online Library
Background Prostate cancer is the most common malignancy among males. Prostaglandin
G/H synthase (PGHS) is an essential enzyme in the synthesis of prostaglandins, and its …
G/H synthase (PGHS) is an essential enzyme in the synthesis of prostaglandins, and its …
Molecular insights into β-Galactosidase enzyme for its potential application in food industry
S Thatikonda, SD Battula, V Syed, K Rasineni… - Journal of the Indian …, 2024 - Elsevier
Abstract β-galactosidase generally catalyzes the hydrolysis of β-d-galactosides and α-L-
arabinosides. β-galactosidases are well known for its wide range of applications in food …
arabinosides. β-galactosidases are well known for its wide range of applications in food …
[HTML][HTML] Identification of potential biomarkers for bone metastasis using human cancer metastasis database
M Bhardwaj, T Sri, S Krupanidhi… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Objective: Information theory has been successfully employed to identify optimal pathway
networks, mutual information (MI), and entropy as a dynamic response in statistical methods …
networks, mutual information (MI), and entropy as a dynamic response in statistical methods …
Nanoproteomics: An Approach for the Identification of Molecular Targets Associated with Hypoxia
A thorough examination of every protein's array in the human proteome is necessary to
understand the causes, pathophysiology, and possible treatment targets of any disease or …
understand the causes, pathophysiology, and possible treatment targets of any disease or …