CCL-11 or eotaxin-1: an immune marker for ageing and accelerated ageing in neuro-psychiatric disorders

M Ivanovska, Z Abdi, M Murdjeva, D Macedo, A Maes… - Pharmaceuticals, 2020 - mdpi.com
Background: CCL-11 (eotaxin) is a chemokine with an important role in allergic conditions.
Recent evidence indicates that CCL-11 plays a role in brain disorders as well. This paper …

TNF-α (G-308A) polymorphism, circulating levels of TNF-α and IGF-1: risk factors for ischemic stroke—an updated meta-analysis

R Duan, N Wang, Y Shang, H Li, Q Liu, L Li… - Frontiers in Aging …, 2022 - frontiersin.org
Objective Accumulated studies have explored gene polymorphisms and circulating levels of
tumor necrosis factor (TNF)-α and insulin-like growth factor (IGF)-1 in the etiology of …

Exploring causal association between circulating inflammatory cytokines and functional outcomes following ischemic stroke: A bidirectional Mendelian randomization …

H Liu, Z Liu, Y Huang, Q Ding, Z Lai… - European Journal of …, 2024 - Wiley Online Library
Objectives Previous observational studies have indicated correlations between various
inflammatory cytokines and functional outcomes following ischemic stroke (IS); however, the …

Gene polymorphisms and circulating levels of the TNF-alpha are associated with ischemic stroke: a meta-analysis based on 19,873 individuals

J Wu, X Zhang, J Wang, Q Liu, X Wang, Z Wu… - International …, 2019 - Elsevier
Objective Numerous studies have investigated associations of gene polymorphisms and
circulating levels of TNF-α with ischemic stroke (IS), but the results were controversial. The …

Knockdown of CC chemokine receptor 5 (CCR5) is protective against cerebral ischemia and reperfusion injury

E Constanza Gomez Victoria… - Current …, 2017 - ingentaconnect.com
Background: Stroke is the second leading cause of death and a major cause of disability of
adults worldwide. Inflammatory processes are known to contribute to the pathophysiology of …

ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta‐analysis

L Karimi, SJ Vijverberg, M Engelkes… - Clinical & …, 2021 - Wiley Online Library
Abstract Background The polymorphism Arg16 in β2‐adrenergic receptor (ADRB2) gene
has been associated with an increased risk of exacerbations in asthmatic children treated …

Resveratrol as a protective molecule for neuroinflammation: a review of mechanisms

J Renaud, MG Martinoli - Current pharmaceutical …, 2014 - ingentaconnect.com
Under normal conditions, most of the central nervous system (CNS) is protected by the blood
brain barrier (BBB) from systemic inflammation progression and from the infiltration of …

Genetic and epigenetic components of aspirin-exacerbated respiratory disease

A Dahlin, ST Weiss - Immunology and Allergy Clinics, 2016 - immunology.theclinics.com
Aspirin intolerance is a severe and rare asthmatic endotype, with prevalence rates of 10% in
the adult asthmatic population and up to 25% in patients with severe, persistent asthma. 1–4 …

Genomics of atrial fibrillation

A Gutierrez, MK Chung - Current cardiology reports, 2016 - Springer
Atrial fibrillation (AF) is a common clinical arrhythmia that appears to be highly heritable,
despite representing a complex interplay of several disease processes that generally do not …

Genetic determinants in ischaemic stroke subtypes: seven year findings and a review

A Munshi, S Das, S Kaul - Gene, 2015 - Elsevier
Stroke is a global health problem and a leading cause of disability worldwide. There have
been numerable studies undertaking research on different aspects of ischaemic stroke …