Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10kDa (IP-
10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family …

Crohn's disease (CD) and ulcerative colitis (UC), two forms of inflammatory bowel disease
(IBD), are chronic, relapsing, and tissue destructive lesions that are accompanied by the …

ABSTRACT A capability for analyzing complex cellular communication among tissues is
important in drug discovery and development, and in vitro technologies for doing so are …

Inflammatory bowel diseases (IBDs) are chronic inflammatory conditions for which new
therapeutic approaches are needed. Genetic and pharmacological data point to a protective …

The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

Epithelial barrier defects are implicated in the pathogenesis of inflammatory bowel disease
(IBD); however, the role of microbiome dysbiosis and the cytokine networks orchestrating …

The traffic of the different types of immune cells is an important aspect in the immune
response. Chemokines are soluble peptides that are able to attract cells by interaction with …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant desmoplastic
reaction driven by pancreatic stellate cells (PSCs) that contributes to tumor progression …

Japanese encephalitis is a neuropathological disorder caused by Japanese encephalitis
virus (JEV), which is characterized by severe pathological neuroinflammation and damage …