Comparative outcome measures in peripheral regeneration studies

SWP Kemp, PS Cederna, R Midha - Experimental neurology, 2017 - Elsevier
Traumatic peripheral nerve injuries are common and often result in partial or permanent
paralysis, numbness of the affected limb, and debilitating neuropathic pain. Experimental …

Facial nerve repair: bioengineering approaches in preclinical models

FB Bengur, C Stoy, MA Binko, WV Nerone… - … Engineering Part B …, 2022 - liebertpub.com
Injury to the facial nerve can occur after different etiologies and range from simple
transection of the branches to varying degrees of segmental loss. Management depends on …

Toward the bionic face: a novel neuroprosthetic device paradigm for facial reanimation consisting of neural blockade and functional electrical stimulation

N Jowett, RE Kearney, CJ Knox… - Plastic and …, 2019 - journals.lww.com
Background: Facial palsy is a devastating condition potentially amenable to rehabilitation by
functional electrical stimulation. Herein, a novel paradigm for unilateral facial reanimation …

Effect of motor versus sensory nerve autografts on regeneration and functional outcomes of rat facial nerve reconstruction

SA Ali, AJ Rosko, JE Hanks, AW Stebbins, O Alkhalili… - Scientific reports, 2019 - nature.com
Cranial nerve injury is disabling for patients, and facial nerve injury is particularly debilitating
due to combined functional impairment and disfigurement. The most widely accepted …

Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair

JJ Greene, MT McClendon… - Journal of tissue …, 2018 - Wiley Online Library
Facial nerve injury can cause severe long‐term physical and psychological morbidity. There
are limited repair options for an acutely transected facial nerve not amenable to primary …

[HTML][HTML] Effects of melatonin and dexamethasone on facial nerve neurorrhaphy

DT Edizer, Z Dönmez, M Gül, Ö Yiğit… - The Journal of …, 2019 - ncbi.nlm.nih.gov
OBJECTIVES To investigate the effects of topical and systemic administrations of melatonin
and dexamethasone on facial nerve regeneration. MATERIALS and METHODS In total, 50 …

Facial nerve surgery in the rat model to study axonal inhibition and regeneration

SA Ali, AW Stebbins, JE Hanks, RA Kupfer… - JoVE (Journal of …, 2020 - jove.com
This protocol describes consistent and reproducible methods to study axonal regeneration
and inhibition in a rat facial nerve injury model. The facial nerve can be manipulated along …

Functional and molecular characterization of a novel traumatic peripheral nerve–muscle injury model

R Wanner, M Gey, A Abaei, D Warnecke… - Neuromolecular …, 2017 - Springer
Traumatic injuries to human peripheral nerves are frequently associated with damage to
nerve surrounding tissues including muscles and blood vessels. Currently, most rodent …

[HTML][HTML] Anatomical description of the extratemporal facial nerve under high-definition system: a microsurgical study in rats

MMR Pinto, DR Santos, LGB Bentes… - Acta Cirúrgica …, 2022 - SciELO Brasil
Purpose: To describe the microsurgical anatomical aspects of the extratemporal facial nerve
of Wistar rats under a high-definition video system. Methods: Ten male Wistar rats (12–15 …

Biodegradable Nerve Guide with Glial Cell Line–Derived Neurotrophic Factor Improves Recovery After Facial Nerve Injury in Rats

FB Bengur, C Komatsu, CN Fedor, S Loder… - Facial Plastic Surgery …, 2023 - liebertpub.com
Background: Bioengineered nerve guides with glial cell line-derived neurotrophic factor
(GDNF) support recovery after facial nerve injury by acting as regenerative scaffolds …