The potential therapeutic use of renin–angiotensin system inhibitors in the treatment of inflammatory diseases

R Ranjbar, M Shafiee, AR Hesari… - Journal of cellular …, 2019 - Wiley Online Library
Inflammation is a normal part of the immune response to injury or infection but its
dysregulation promotes the development of inflammatory diseases, which cause …

[HTML][HTML] Immunomodulatory Activity of the Most Commonly Used Antihypertensive Drugs—Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor …

P Bryniarski, K Nazimek, J Marcinkiewicz - International Journal of …, 2022 - mdpi.com
This review article is focused on antihypertensive drugs, namely angiotensin converting
enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB), and their …

Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice

K Amirshahrokhi - International Immunopharmacology, 2019 - Elsevier
Ulcerative colitis is a chronic inflammatory disorder characterized by oxidative stress and
upregulation of proinflammatory mediators in colonic tissue. Febuxostat, a xanthine oxidase …

[HTML][HTML] Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments

C Chen, H Zhang, H Xu, Y Zheng, T Wu… - Journal of ginseng …, 2019 - Elsevier
Abstract Background Ginsenoside Rb1 (Rb1), a dominant component from the extract of
Panax ginseng root, exhibits neuroprotective functions in many neurological diseases. This …

Methylsulfonylmethane is effective against gastric mucosal injury

K Amirshahrokhi, AR Khalili - European journal of pharmacology, 2017 - Elsevier
Methylsulfonylmethane (MSM) is a natural organosulfur compound has been widely used as
a dietary supplement. MSM has protective effects against various disorders through its anti …

Hepatoprotective effects of selenium-enriched probiotics supplementation on heat-stressed wistar rat through anti-inflammatory and antioxidant effects

RM Malyar, E Naseri, H Li, I Ali, RA Farid, D Liu… - … Trace Element Research, 2021 - Springer
The purpose of this study was to elucidate the effects of selenium-enriched probiotics on the
liver of heat-stressed Wistar rats. Ten-week-old male rats were assigned to four groups …

Thalidomide ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in an experimental model

K Amirshahrokhi, AR Khalili - Inflammation, 2015 - Springer
Cisplatin is a platinum-based chemotherapy drug. However, its chemotherapeutic use is
restricted by serious side effects, especially nephrotoxicity. Inflammatory mechanisms have …

The effects of captopril on lipopolysaccharide induced learning and memory impairments and the brain cytokine levels and oxidative damage in rats

A Abareshi, M Hosseini, F Beheshti, F Norouzi… - Life sciences, 2016 - Elsevier
Aim Renin-angiotensin system has a role in inflammation and also involves in learning and
memory. In the present study, the effects of captopril on lipopolysaccharide (LPS) induced …

Lipopolysaccharide‐induced spatial memory and synaptic plasticity impairment is preventable by captopril

A Abareshi, A Anaeigoudari, F Norouzi… - Advances in …, 2016 - Wiley Online Library
Introduction. Renin‐angiotensin system has a role in inflammation and also is involved in
many brain functions such as learning, memory, and emotion. Neuroimmune factors have …

[PDF][PDF] Fasudil alleviates hepatic fibrosis in type 1 diabetic rats: involvement of the inflammation and RhoA/ROCK pathway.

Y Xie, T Song, M Huo, Y Zhang… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Rho-associated kinases (ROCKs) are recognized to be involved in many
pathophysiological processes caused by hyperglycemia. We performed experiments to …