Therapeutic potential and biological applications of cordycepin and metabolic mechanisms in cordycepin-producing fungi

P Qin, XK Li, H Yang, ZY Wang, DX Lu - Molecules, 2019 - mdpi.com
Cordycepin (3′-deoxyadenosine), a cytotoxic nucleoside analogue found in Cordyceps
militaris, has attracted much attention due to its therapeutic potential and biological value …

Biomass and Cordycepin Production by the Medicinal Mushroom Cordyceps militaris—A Review of Various Aspects and Recent Trends towards the Exploitation of a …

D Kontogiannatos, G Koutrotsios, S Xekalaki… - Journal of Fungi, 2021 - mdpi.com
Cordyceps militaris is an entomopathogenic ascomycete with similar pharmacological
importance to that of the wild caterpillar fungus Ophiocordyceps sinensis. C. militaris has …

High-level production of cordycepin by the xylose-utilising Cordyceps militaris strain 147 in an optimised medium

L Long, Z Liu, Y Wang, Q Lin, S Ding, C Li… - Bioresource …, 2023 - Elsevier
Cordycepin is an important active metabolite of Cordyceps militaris. Xylose, an attractive
feedstock for producing chemicals through microbial fermentation, cannot be effectively …

Microbial synthesis of cordycepin, current systems and future perspectives

X Duan, H Yang, C Wang, H Liu, X Lu, Y Tian - Trends in Food Science & …, 2023 - Elsevier
Background Cordycepin is one of the nucleoside compounds with various nutraceutical and
health-promoting functions, which makes it widely used in nutraceutical and pharmaceutical …

Comparison of chemical profiles, antioxidation, inhibition of skin extracellular matrix degradation, and anti-tyrosinase activity between mycelium and fruiting body of …

A Prommaban, S Sriyab, P Marsup… - Pharmaceutical …, 2022 - Taylor & Francis
Abstract Context Cordyceps militaris and Isaria tenuipes (Cordycipitaceae) are high-value
fungi that are used for health-promoting food supplements. Since laboratory cultivation has …

[HTML][HTML] Enhanced production of cordycepin in Ophiocordyceps sinensis using growth supplements under submerged conditions

V Kaushik, A Singh, A Arya, SC Sindhu, A Sindhu… - Biotechnology …, 2020 - Elsevier
Cordycepin is a crucial bioactive compound produced by the fungus Cordyceps spp. Its
therapeutic potential has been recognized for a wide range of biological properties such as …

Uncovering global metabolic response to cordycepin production in Cordyceps militaris through transcriptome and genome-scale network-driven analysis

N Raethong, K Laoteng, W Vongsangnak - Scientific reports, 2018 - nature.com
The cellular metabolic adaptations of Cordyceps militaris have been progressively studied.
In particular, the cordycepin pathway is of interest in medicinal applications. Even though the …

[HTML][HTML] Alternative metabolic routes in channeling xylose to cordycepin production of Cordyceps militaris identified by comparative transcriptome analysis

B Wongsa, N Raethong, P Chumnanpuen… - Genomics, 2020 - Elsevier
The responsive mechanism of C. militaris TBRC7358 on xylose utilization was investigated
by comparative analysis of transcriptomes, growth kinetics and cordycepin productions. The …

Effect of Air Drying on the Metabolic Profile of Fresh Wild and Artificial Cordyceps sinensis

T Wang, C Tang, M Xiao, Z Cao, M He, J Qi, Y Li, X Li - Foods, 2023 - mdpi.com
Fresh and dried Cordyceps sinensis are widely used by the public for medicinal and health
purposes. However, the differences between them have not been examined. In this study …

Research Progress in Understanding the Molecular Biology of Cordyceps militaris

L Wang, G Li, X Tian, Y Shang, H Yan, L Yao, Z Hu - Fermentation, 2024 - mdpi.com
Cordyceps militaris (C. militaris) is a valued medicinal fungus that can be traced back
thousands of years in traditional Chinese medicine (TCM). Both TCM and modern scientific …