Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis
D Cimadomo, L Rienzi, A Conforti… - Human …, 2023 - academic.oup.com
BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …
Advanced maternal age in IVF: still a challenge? The present and the future of its treatment
FM Ubaldi, D Cimadomo, A Vaiarelli… - Frontiers in …, 2019 - frontiersin.org
Advanced maternal age (AMA;> 35 year) is associated with a decline in both ovarian
reserve and oocyte competence. At present, no remedies are available to counteract the …
reserve and oocyte competence. At present, no remedies are available to counteract the …
The impact of biopsy on human embryo developmental potential during preimplantation genetic diagnosis
D Cimadomo, A Capalbo, FM Ubaldi… - BioMed research …, 2016 - Wiley Online Library
Preimplantation Genetic Diagnosis and Screening (PGD/PGS) for monogenic diseases
and/or numerical/structural chromosomal abnormalities is a tool for embryo testing aimed at …
and/or numerical/structural chromosomal abnormalities is a tool for embryo testing aimed at …
Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging
A Capalbo, ER Hoffmann, D Cimadomo… - Human reproduction …, 2017 - academic.oup.com
ABSTRACT BACKGROUND The unbalanced transmission of chromosomes in human
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …
[HTML][HTML] Optimal euploid embryo transfer strategy, fresh versus frozen, after preimplantation genetic screening with next generation sequencing: a randomized …
A Coates, A Kung, E Mounts, J Hesla, B Bankowski… - Fertility and sterility, 2017 - Elsevier
Objective To compare two commonly used protocols (fresh vs. vitrified) used to transfer
euploid blastocysts after IVF with preimplantation genetic screening. Design Randomized …
euploid blastocysts after IVF with preimplantation genetic screening. Design Randomized …
[HTML][HTML] Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications
C Rubio, L Rienzi, L Navarro-Sánchez, D Cimadomo… - Fertility and sterility, 2019 - Elsevier
Objective To study whether embryonic cell-free DNA (cfDNA) in spent blastocyst media is
representative of the chromosomal constitution of a blastocyst. Design Pilot prospective …
representative of the chromosomal constitution of a blastocyst. Design Pilot prospective …
[HTML][HTML] Proof of concept: preimplantation genetic screening without embryo biopsy through analysis of cell-free DNA in spent embryo culture media
MI Shamonki, H Jin, Z Haimowitz, L Liu - Fertility and sterility, 2016 - Elsevier
Objective To assess whether preimplantation genetic screening (PGS) is possible by testing
for free embryonic DNA in spent IVF media from embryos undergoing trophectoderm biopsy …
for free embryonic DNA in spent IVF media from embryos undergoing trophectoderm biopsy …
The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists
K Sermon, A Capalbo, J Cohen… - MHR: Basic science …, 2016 - academic.oup.com
STUDY QUESTION We wanted to probe the opinions and current practices on
preimplantation genetic screening (PGS), and more specifically on PGS in its newest form …
preimplantation genetic screening (PGS), and more specifically on PGS in its newest form …
Incidence, origin, and predictive model for the detection and clinical management of segmental aneuploidies in human embryos
L Girardi, M Serdarogullari, C Patassini, M Poli… - The American Journal of …, 2020 - cell.com
Despite next-generation sequencing, which now allows for the accurate detection of
segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and …
segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and …
Influence of cryopreservation on perinatal outcome after blastocyst‐ vs cleavage‐stage embryo transfer: systematic review and meta‐analysis
C Alviggi, A Conforti, IF Carbone… - … in Obstetrics & …, 2018 - Wiley Online Library
Objective To compare the perinatal outcomes of singleton pregnancies resulting from
blastocyst‐vs cleavage‐stage embryo transfer and to assess whether they differ between …
blastocyst‐vs cleavage‐stage embryo transfer and to assess whether they differ between …