Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 2008 - pubs.rsc.org
Covering: July 2005 to June 2006. Previous review: Nat. Prod. Rep., 2007, 24, 223–246 This
review covers the isolation, structure determination, synthesis and biological activity of …

Roles of pyridine and pyrimidine derivatives as privileged scaffolds in anticancer agents

S Prachayasittikul, R Pingaew… - Mini Reviews in …, 2017 - ingentaconnect.com
Background: Cancer has been considered to be a global health concern due to the impact of
disease on the quality of life. The continual increase of cancer cases as well as the …

In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives

KCS Achar, KM Hosamani… - European journal of …, 2010 - Elsevier
A series of 2-methylaminobenzimidazole derivatives (1–11) were synthesized by the
reaction of 2-(chloromethyl)-1H-benzimidazole derivatives with primary aromatic amines. All …

Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV

J Feng, Z Zhang, MB Wallace, JA Stafford… - Journal of medicinal …, 2007 - ACS Publications
Alogliptin is a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-
4). Herein, we describe the structure-based design and optimization of alogliptin and related …

Metal-Free Photoinduced Hydrocyclization of Unactivated Alkenes toward Ring-Fused Quinazolin-4(3H)-ones via Intermolecular Hydrogen Atom Transfer

Z Yang, X Wu, J Zhang, JT Yu, C Pan - Organic Letters, 2023 - ACS Publications
A visible-light-induced hydrocyclization of unactivated alkenes was developed using
3CzClIPN as the photocatalyst to generate substituted α-methyldeoxyvasicinones and α …

Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones

SK Singh, S Kumar, MS Yadav… - The Journal of Organic …, 2022 - ACS Publications
The glycosyl 1, 2, 3-triazoles are expediently accessible from readily available sugar-
derived glycosyl azide by utilizing modular CuAAC “Click Chemistry”, and the resulting …

Microwave-assisted one step high-throughput synthesis of benzimidazoles

SY Lin, Y Isome, E Stewart, JF Liu, D Yohannes, L Yu - Tetrahedron Letters, 2006 - Elsevier
Microwave-assisted one step high-throughput synthesis of benzimidazoles - ScienceDirect
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[HTML][HTML] Synthesis and biological evaluation studies of novel quinazolinone derivatives as antibacterial and anti-inflammatory agents

MF Zayed, MH Hassan - Saudi pharmaceutical journal, 2014 - Elsevier
Abstract Some novel 6, 8-diiodo-2-methyl-3-substituted-quinazolin-4 (3H)-ones bearing
sulfonamide derivatives (4–11) were synthesized in good yields and evaluated for their …

Remarkably flexible quinazolinones—synthesis and biological applications

MM Reddy, A Sivaramakrishna - Journal of Heterocyclic …, 2020 - Wiley Online Library
Even though several quinazolinone derivatives have been synthesized, still there is a
constant demand for designing and synthesis of new quinazolinone derivatives by fine …

Survey of recent literature related to the biologically active 4 (3H)-quinazolinones containing fused heterocycles

M Demeunynck, I Baussanne - Current medicinal chemistry, 2013 - ingentaconnect.com
the present review focuses on the synthesis and biological evaluation of polycyclic 4 (3H)-
quinazolinones containing fused aromatic or heteroaromatic rings. The first part of the …