Salivary glands concentrate plasma nitrate into saliva, leading to high nitrate concentrations
that can reach the millimolar range after a nitrate-rich vegetable meal. Whereas human cells …

Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …

The salivary glands actively concentrate plasma nitrate, leading to high salivary nitrate
concentrations (5–8 mM) after a nitrate-rich vegetable meal. Nitrate is an ecological factor …

The use of nitric oxide (NO) is emerging as a promising, novel approach for the treatment of
antibiotic resistant bacteria and biofilm infections. Depending on the concentration, NO can …

Exogenous nitric oxide (NO) represents an attractive antibacterial agent because of its ability
to both disperse and directly kill bacterial biofilms while avoiding resistance. Due to the …

The alarming increase in antimicrobial resistance, based on the built-in abilities of bacteria
to nullify the activity of current antibiotics, leaves a growing number of bacterial infections …

Recent evidence indicates that the reduction of salivary nitrate by oral bacteria can
contribute to prevent oral diseases, as well as increase systemic nitric oxide levels that can …

A few studies indicate that nitrate can reduce dysbiosis from a periodontitis point of view.
However, these experiments were performed on samples from healthy individuals, and it is …

Demineralization and breakdown of tooth enamel are characterized by a condition called
dental caries or tooth decay, which is caused by two main factors:(1) highly acidic food …

The reduction of nitrate to nitrite by the oral microbiota has been proposed to be important
for oral health and results in nitric oxide formation that can improve cardiometabolic …