COVID-19 annual update: a narrative review

M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Drug treatment of COVID-19 infection

G Lui, G Guaraldi - Current opinion in pulmonary medicine, 2023 - journals.lww.com
Drug treatment of COVID-19 infection : Current Opinion in Pulmonary Medicine Drug treatment
of COVID-19 infection : Current Opinion in Pulmonary Medicine Log in or Register Subscribe to …

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

G Grasselli, CS Calfee, L Camporota, D Poole… - Intensive care …, 2023 - Springer
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the
European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to …

[HTML][HTML] Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised …

RECOVERY Collaborative Group - Lancet (London, England), 2023 - ncbi.nlm.nih.gov
Background Low-dose corticosteroids have been shown to reduce mortality for patients with
COVID-19 requiring oxygen or ventilatory support (non-invasive mechanical ventilation …

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised …

O Abani, A Abbas, F Abbas, J Abbas, K Abbas… - The Lancet, 2023 - thelancet.com
Background Low-dose corticosteroids have been shown to reduce mortality for patients with
COVID-19 requiring oxygen or ventilatory support (non-invasive mechanical ventilation …

Acute lung injury caused by sepsis: how does it happen?

B Sun, M Lei, J Zhang, H Kang, H Liu, F Zhou - Frontiers in Medicine, 2023 - frontiersin.org
Sepsis is a systemic inflammatory disease caused by severe infections that involves multiple
systemic organs, among which the lung is the most susceptible, leaving patients highly …

Corticosteroids in ARDS

E Kuperminc, N Heming, M Carlos… - Journal of Clinical …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is frequently associated with sepsis. ARDS and
sepsis exhibit a common pathobiology, namely excessive inflammation. Corticosteroids are …

Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Evaluation of the drug–drug interaction potential of ensitrelvir fumaric acid with cytochrome P450 3A substrates in healthy Japanese adults

R Shimizu, T Sonoyama, T Fukuhara, A Kuwata… - Clinical Drug …, 2023 - Springer
Background Management of drug–drug interactions (DDIs) for ensitrelvir, a novel 3-
chymotrypsin-like protease inhibitor of SARS-CoV-2 infection is crucial. A previous clinical …

Low-dose versus high-dose dexamethasone for hospitalized patients with COVID-19 pneumonia: a randomized clinical trial

H Wu, S Daouk, J Kebbe, F Chaudry, J Harper… - PloS one, 2022 - journals.plos.org
Background Dexamethasone 6 mg daily for 10 days is the recommended treatment for
patients with severe or critical coronavirus disease 2019 (COVID-19). The evidence on the …