Role of calcimimetics in treating bone and mineral disorders related to chronic kidney disease

YC Hou, CM Zheng, HW Chiu, WC Liu, KC Lu, CL Lu - Pharmaceuticals, 2022 - mdpi.com
Renal osteodystrophy is common in patients with chronic kidney disease and end-stage
renal disease and leads to the risks of fracture and extraosseous vascular calcification …

Update on chronic kidney disease mineral and bone disorder in cardiovascular disease

J Lunyera, JJ Scialla - Seminars in nephrology, 2018 - Elsevier
Chronic kidney disease mineral and bone disorder (MBD) encompasses changes in mineral
ion and vitamin D metabolism that are widespread in the setting of chronic kidney disease …

Personalized management of bone and mineral disorders and precision medicine in end-stage kidney disease

A Jovanovich, J Kendrick - Seminars in nephrology, 2018 - Elsevier
Chronic kidney disease mineral bone disorder (CKD-MBD) is common in end-stage renal
disease and is associated with an increased risk of cardiovascular morbidity and mortality …

The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism

J Ngamkam, S Vadcharavivad, N Areepium… - Scientific Reports, 2021 - nature.com
The objective of this study was to determine the impact of calcium sensing receptor (CASR)
A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to …

Evaluation of the interaction of cinacalcet with calf thymus dsDNA: Use of electrochemical, spectrofluorimetric, and molecular docking methods

C Erkmen, DN Unal, S Kurbanoglu, G Eren, B Uslu - Biosensors, 2022 - mdpi.com
The binding of drugs to DNA plays a critical role in new drug discovery and is important for
designing better drugs. In this study, the interaction and binding mode of calf-thymus double …

Impact of Cinacalcet and Etelcalcetide on Bone Mineral and Cardiovascular Disease in Dialysis Patients

J Bernardor, A De Mul, J Bacchetta… - Current Osteoporosis …, 2023 - Springer
Abstract Purposes of Review With chronic kidney disease (CKD) progression, secondary
hyperparathyroidism (sHPT) and mineral and bone metabolism disease (MBD) almost …

Genetic variants associated with mineral metabolism traits in chronic kidney disease

ML Laster, B Rowan, HC Chen… - The Journal of …, 2022 - academic.oup.com
Context Chronic kidney disease (CKD) causes multiple interrelated disturbances in mineral
metabolism. Genetic studies in the general population have identified common genetic …

Current treatment options for secondary hyperparathyroidism in patients with stage 3 to 4 chronic kidney disease and vitamin D deficiency

A Galassi, P Ciceri, G Porata, R Iatrino… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Secondary hyperparathyroidism (SHPT) represents a complication of chronic
kidney disease (CKD). Vitamin D system is altered since early CKD, and vitamin D …

[HTML][HTML] Rationale to reduce calcium intake in patients with CKD

SM Moe - Current opinion in nephrology and hypertension, 2018 - ncbi.nlm.nih.gov
Rationale to reduce calcium intake in patients with CKD - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Haplotype of CaSR gene is associated with risk of renal stone disease in West Indian population

YP Patel, SN Pandey, SB Patel, A Parikh, S Soni… - Urolithiasis, 2022 - Springer
Calcium is the most abundant metabolite involved in the stone matrix. The CaSR gene
controls calcium homeostasis, and genetic variation in the CaSR gene could lead to the …