A community-based sessile life style is the normal mode of growth and survival for many
bacterial species. Under such conditions, cell-to-cell interactions are inevitable and …

Bacterial adhesion has become a significant problem in industry and in the domicile, and
much research has been done for deeper understanding of the processes involved. A …

Bone and joint infections are painful for patients and frustrating for both them and their
doctors. The high success rates of antimicrobial therapy in most infectious diseases have not …

Nearly 40 years ago, Dr. RJ Gibbons made the first reports of the clinical relevance of what
we now know as bacterial biofilms when he published his observations of the role of …

Teichoic acids (TAs) are major wall and membrane components of most gram-positive
bacteria. With few exceptions, they are polymers of glycerol-phosphate or ribitol-phosphate …

Pseudomonas aeruginosa is an important pathogen causing a wide range of acute and
chronic infections. P. aeruginosa rarely causes infection in the normal host, but is an efficient …

Several serious diseases are caused by biofilm-associated Staphylococcus aureus,
infections in which the accessory gene regulator (agr) quorum-sensing system is thought to …

We have studied the diffusion of tracer proteins in highly concentrated random-coil polymer
and globular protein solutions imitating the crowded conditions encountered in cellular …

Staphylococcus aureus (S. aureus) readily forms biofilms on prosthetic devices such as the
pacemakers, heart valves, orthopaedic implants, and indwelling catheters. Its biofilms are …

While studying virulence gene regulation in Vibrio cholerae during infection of the host small
intestine, we identified VieA as a two‐component response regulator that contributes to …