Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …

Nanomaterials have been extensively used for cancer therapy and diagnosis due to their
designability, multifunctionality, and unique in vivo distribution. Metal ions are increasingly …

Metabolic reprogramming is one of the most important hallmarks of malignant tumors.
Specifically, lipid metabolic reprogramming has marked impacts on cancer progression and …

As a necessary substance to maintain the body's normal life activities, metal ions are
ubiquitous in organisms and play a major role in various complex physiological and …

In their seminal papers Hanahan and Weinberg described oncogenic processes a normal
cell undergoes to be transformed into a cancer cell. The functions of ion channels in the …

Despite the development of a number of vaccines for COVID-19, there remains a need for
prevention and treatment of the virus SARS-CoV-2 and the ensuing disease COVID-19. This …

In non-excitable cells, Orai proteins represent the main channel for Store-Operated Calcium
Entry (SOCE), and also mediate various store-independent Calcium Entry (SICE) pathways …

Calcium research, since its pivotal discovery in the early 1800s through the heating of
limestone, has led to the identification of its multi-functional roles. These include its functions …

Cancer is a major cause of death. The diversity of cancer types and the propensity of
cancers to acquire resistance to therapies, including new molecularly targeted and immune …

Zinc, an indispensable micronutrient for human health, might play an important role in the
development of atherosclerosis. Zinc could be involved in the atherogenic process through …