A growing body of evidence indicates that, over the course of evolution of the immune
system, arginine has been selected as a node for the regulation of immune responses. An …

Tumor-associated myeloid cells (TAMCs) are among the most important immune cell
populations in the tumor microenvironment, and play a significant role on the efficacy of …

SARS-CoV-2 infection is associated with lower blood oxygen levels, even in patients without
hypoxia requiring hospitalization. This discordance illustrates the need for a more unifying …

Understanding the function of SARS-CoV-2 Ag-specific T cells is crucial for the monitoring of
antiviral immunity and vaccine design. Currently, both impaired and robust T cell immunity is …

Complex regulation of the immune response is necessary to support effective defense of an
organism against hostile invaders and to maintain tolerance to harmless microorganisms …

Preterm infants are at increased risk for invasive neonatal bacterial infections. S.
epidermidis, a ubiquitous skin commensal, is a major cause of late-onset neonatal sepsis …

Abstract CD45+ CD71+ erythroid cells generated through splenic extramedullary
erythropoiesis have recently been found to suppress anti-infection and tumor immunity in …

We report significant upregulation of Galectin-9 (Gal-9) and VISTA on both CD4+ and CD8+
T cells in HIV-infected human patients. Gal-9 and VISTA expression was associated with …

Newborns are highly susceptible to infectious diseases. The underlying mechanism of
neonatal infection susceptibility has generally been related to their under-developed …

Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer.
However, only a portion of patients respond to such treatments. Therefore, it remains a …