Challenges in developing cell culture media using machine learning

T Hashizume, BW Ying - Biotechnology Advances, 2024 - Elsevier
Microbial and mammalian cells are widely used in the food, pharmaceutical, and medical
industries. Developing or optimizing culture media is essential to improve cell culture …

Recent progress towards industrial rhamnolipids fermentation: process optimization and foam control

J Jiang, Y Zu, X Li, Q Meng, X Long - Bioresource technology, 2020 - Elsevier
The global market for rhamnolipids production holds great promise, and is in need of an
economically viable mass-production scheme. Accordingly, several strategies have been …

Systematic optimization of a novel, cost-effective fermentation medium of Sporosarcina pasteurii for microbially induced calcite precipitation (MICP)

L Chen, Y Song, H Fang, Q Feng, C Lai… - Construction and Building …, 2022 - Elsevier
Microbially induced calcite precipitation (MICP) is a promising technology for sand fixation,
ground stabilisation, concrete crack repairment, and contaminated soil remediation …

Biosurfactants: research trends and applications

CN Mulligan, SK Sharma, A Mudhoo - 2014 - books.google.com
Microbially derived surfactants, called biosurfactants, provide a promising alternative to
synthetic surfactants, displaying better availability and being generally nontoxic and …

Statistical modelling and optimization of protease production by an autochthonous Bacillus aryabhattai Ab15-ES: A response surface methodology approach

AI Adetunji, AO Olaniran - Biocatalysis and Agricultural Biotechnology, 2020 - Elsevier
In this study, response surface methodology (RSM) was employed for the optimization of
bioprocess parameters for enhanced extracellular protease production by a native Bacillus …

Bioprospecting of rhamnolipids production and optimization by an oil-degrading Pseudomonas sp. S2WE isolated from freshwater lake

IA Phulpoto, Y Wang, MA Qazi, B Hu… - Bioresource …, 2021 - Elsevier
The present study revealed biosurfactants production by a novel oil-degrading
Pseudomonas sp. S2WE isolated from hydrocarbon enriched water sample, where the …

A review of algorithmic approaches for cell culture media optimization

T Zhou, R Reji, RS Kairon, KH Chiam - Frontiers in Bioengineering …, 2023 - frontiersin.org
Cell culture media composition and culture conditions play a crucial role in product yield,
quality and cost of production. Culture media optimization is the technique of improving …

Simulated annealing and artificial neural network as optimization tools to enhance yields of bioemulsifier and exopolysaccharides by thermophilic Brevibacillus …

S Dhagat, SE Jujjavarapu - Journal of Environmental Chemical …, 2021 - Elsevier
Bioemulsifiers and exopolysaccharides are industrially important biomolecules that are
produced by microbial fermentation and have applications in food, cosmetics and …

Chitin from seafood waste: particle swarm optimization and neural network study for the improved chitinase production

N Suryawanshi, JS Eswari - Journal of Chemical Technology & …, 2022 - Wiley Online Library
BACKGROUND The current system in the processing of seafood leads to accumulation of
many waste products, such as shells, tails, heads and bones. This seafood waste can be …

Toward high-efficiency production of biosurfactant rhamnolipids using sequential fed-batch fermentation based on a fill-and-draw strategy

N He, T Wu, J Jiang, X Long, B Shao, Q Meng - Colloids and Surfaces B …, 2017 - Elsevier
Rhamnolipids are the most promising biosurfactants, have widespread applications in many
fields. However, low yield and productivity in fermentation caused a high production cost …