CFTR modulator therapies: potential impact on airway infections in cystic fibrosis

F Saluzzo, L Riberi, B Messore, NI Loré, I Esposito… - Cells, 2022 - mdpi.com
Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene
encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein …

Superantigens, a paradox of the immune response

S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …

Genotypic and phenotypic diversity of Staphylococcus aureus isolates from cystic fibrosis patient lung infections and their interactions with Pseudomonas aeruginosa

EE Bernardy, RA Petit III, V Raghuram, AM Alexander… - MBio, 2020 - Am Soc Microbiol
Staphylococcus aureus has recently overtaken Pseudomonas aeruginosa as the most
commonly recognized bacterial pathogen that infects the respiratory tracts of individuals with …

Presence of egc-positive major clones ST 45, 30 and 22 among methicillin-resistant and methicillin-susceptible oral Staphylococcusaureus strains

E Kwapisz, K Garbacz, M Kosecka-Strojek… - Scientific Reports, 2020 - nature.com
The oral cavity may comprise a significant reservoir for Staphylococcus aureus but the data
on molecular epidemiology and clonal distribution of oral strains are really scarce. This …

Investigation into the prevalence of enterotoxin genes and genetic background of Staphylococcus aureus isolates from retain foods in Hangzhou, China

Q Chen, G Zhao, W Yang, F Chen, Y Qi, Z Lou - BMC microbiology, 2023 - Springer
Background Staphylococcus aureus expresses numerous toxins, many of which are strongly
believed to be responsible for specific symptoms and even diseases, making it significant in …

High Prevalence of Staphylococcus aureus Enterotoxin Gene Cluster Superantigens in Cystic Fibrosis Clinical Isolates

AJ Fischer, SH Kilgore, SB Singh, PD Allen… - Genes, 2019 - mdpi.com
Background: Staphylococcus aureus is a highly prevalent respiratory pathogen in cystic
fibrosis (CF). It is unclear how this organism establishes chronic infections in CF airways. We …

[HTML][HTML] Livestock associated Staphylococcus aureus in cystic fibrosis patients in Spain: Detection of MRSA and MSSA CC398

P Eguizábal, AI López-Calleja, A Arias… - Microbial …, 2024 - Elsevier
Purpose Staphylococcus aureus is one of the most prevalent pathogens in cystic fibrosis
(CF), being of special relevance those methicillin-resistant (MRSA). The livestock-associated …

Multi-Host Pathogen Staphylococcus aureus—Epidemiology, Drug Resistance and Occurrence in Humans and Animals in Poland

A Trościańczyk, A Nowakiewicz, M Kasela, A Malm… - Antibiotics, 2023 - mdpi.com
Staphylococcus aureus is a drug resistant pathogen with zoonotic potential commonly
isolated from humans and animals. The aim of this study was to compare the occurrence of …

Limited evidence of patient-to-patient transmission of Staphylococcus aureus strains between children with cystic fibrosis, Queensland, Australia

SL Biggs, AV Jennison, H Bergh, R Graham, G Nimmo… - Plos one, 2022 - journals.plos.org
Objectives Here we used whole genome sequencing (WGS) to understand strain diversity
and potential for patient-to-patient transmission of Staphylococcus aureus among children …

Genetic diversity and antimicrobial resistance of Staphylococcus aureus from recurrent tonsillitis in children

M Katkowska, K Garbacz, W Kopala, J Schubert… - Apmis, 2020 - Wiley Online Library
The aim of this study was to analyze the prevalence of Staphylococcus aureus in the tonsils
of children subjected tonsillectomy due to recurrent tonsilitis and to determine the spa types …