Cells are inherently dynamic, whether they are responding to environmental conditions or
simply at equilibrium, with biomolecules constantly being made and destroyed. Due to their …

Intracellular reaction rates depend on concentrations and hence their levels are often
regulated. However classical models of stochastic gene expression lack a cell size …

The stochasticity of gene expression is manifested in the fluctuations of messenger
ribonucleic acid and protein copy numbers within a cell lineage over time. While data of this …

Heterogeneity in the size distribution of cancer cell populations is linked to drug resistance
and invasiveness. However, understanding how such heterogeneity arises is still damped …

Recent advances in single-cell technologies have enabled time-resolved measurements of
the cell size over several cell cycles. These data encode information on how cells correct …

Under ideal conditions, Escherichia coli cells divide after adding a fixed cell size, a strategy
known as the adder. This concept applies to various microbes and is often explained as the …

We examine five quantitative models of the cell-cycle and cell-size control in Escherichia coli
and Bacillus subtilis that have been proposed over the last decade to explain single-cell …

Almost all living cells maintain size uniformity through successive divisions. Proteins that
over and underscale with size can act as rheostats, which regulate cell cycle progression …

We derive analytical steady-state cell size distributions for size-controlled cells in single-
lineage experiments, such as the mother machine, which are fundamentally different from …

The dynamics of the size distribution in growing and dividing rod-shaped bacteria can
change depending on the perspective through which the cell population is observed. From …