Testing for anti-RNA polymerase III antibodies should be incorporated into clinical care to
identify patients at high risk for SRC. Recommendations from European League Against …

The spectrum of kidney involvement in systemic sclerosis (SSc) includes scleroderma renal
crisis, widely recognized as the most severe renal-vascular complication, but also several …

Among all possible systemic sclerosis internal organ complications, kidney involvement is
frequently neglected or underestimated, except for the life-threatening scleroderma renal …

Aim Endothelial dysfunction and microvascular damage are hallmarks of systemic sclerosis
(SSc). Objective of this study was to evaluate IL33 and ST2 serum levels in SSc patients and …

Background: Many patients admitted to a Department of Internal Medicine have different
degrees of heart and kidney dysfunction. Mortality, morbidity and cost of care greatly …

Abstract Background/Aims: Renal involvement is common in systemic sclerosis (SSc),
including asymptomatic reduction of glomerular filtration rate (GFR), increased renal …

Circulating free light chains (FLCs), considered biomarkers of B cell activity, are frequently
elevated in patients affected by systemic inflammatory autoimmune diseases. As the …

Research regarding renal involvement in SSc has almost exclusively focused on
scleroderma renal crisis (SRC). There are relatively limited data regarding renal impairment …

Background Microvascular damage of skin and internal organs is a hallmark of systemic
sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial …

Background The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-
angiogenic factors and angiogenesis inhibitors has been implicated in the progression of …