The environmental and health impacts from the massive discharge of chemicals and
subsequent pollution have been gaining increasing public concern. The unintended …

The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Obesity is a major global health problem and predisposes individuals to several
comorbidities that can affect life expectancy. Interventions based on lifestyle modification (for …

Accumulated evidence from genetic animal models suggests that the brain, particularly the
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …

The brain hypothalamus contains certain secreted molecules that are important in regulating
feeding behaviour,,. Here we show that nesfatin, corresponding to NEFA/nucleobindin2 …

A large body of research has been dedicated to the effects of gastrointestinal peptides on
vagal afferent fibres, yet multiple lines of evidence indicate that gastrointestinal peptides …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

Background: The exclusion of the proximal small intestine is thought to play a major role in
the rapid improvement in the metabolic control of diabetes after gastric bypass. Objective: In …

Rationale Early life stress has been implicated in many psychiatric disorders ranging from
depression to anxiety. Maternal separation in rodents is a well-studied model of early life …

Polycystic ovary syndrome (PCOS) is the most common, heterogeneous, and multifactorial
endocrine disorder in premenopausal women. The pathophysiology of this endocrinopathy …