Extra-skeletal effects of vitamin D

R Marino, M Misra - Nutrients, 2019 - mdpi.com
The vitamin D receptor is expressed in multiple cells of the body (other than osteoblasts),
including beta cells and cells involved in immune modulation (such as mononuclear cells …

Vitamin D supplementation and cancer mortality: narrative review of observational studies and clinical trials

P Gnagnarella, V Muzio, S Caini, S Raimondi… - Nutrients, 2021 - mdpi.com
Several studies have investigated the beneficial effects of vitamin D on survival of cancer
patients. Overall evidence has been accumulating with contrasting results. This paper aims …

Long-Term Effect of Randomization to Calcium and Vitamin D Supplementation on Health in Older Women: Postintervention Follow-up of a Randomized Clinical Trial

CA Thomson, AK Aragaki, RL Prentice… - Annals of internal …, 2024 - acpjournals.org
Background: Although calcium and vitamin D (CaD) supplementation may affect chronic
disease in older women, evidence of long-term effects on health outcomes is limited …

From molecular basis to clinical insights: a challenging future for the vitamin D endocrine system in colorectal cancer

F Pereira, A Fernández‐Barral, MJ Larriba… - The FEBS …, 2024 - Wiley Online Library
Colorectal cancer (CRC) is one of the most life‐threatening neoplasias in terms of incidence
and mortality worldwide. Vitamin D deficiency has been associated with an increased risk of …

Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology

M Scuto, AT Salinaro, I Caligiuri, ML Ontario… - Mechanisms of Ageing …, 2021 - Elsevier
Polyphenols are chemopreventive through the induction of nuclear factor erythroid 2 related
factor 2 (Nrf2)-mediated proteins and anti-inflammatory pathways. These pathways …

Vitamin D and cancer survival: does vitamin D supplementation improve the survival of patients with cancer?

T Akutsu, H Kitamura, S Himeiwa, S Kitada… - Current oncology …, 2020 - Springer
Abstract Purpose of Review Clinical evidence suggesting the beneficial effects of vitamin D
on survival of patients with cancer has been accumulating. Recent articles were thoroughly …

Role of BCL-2 family proteins in apoptosis and its regulation by nutrients

C Zheng, T Liu, H Liu, J Wang - Current Protein and Peptide …, 2020 - ingentaconnect.com
In the body, millions of cells die and proliferate each day to maintain normal function and
cooperation of all tissues, organs, and systems. Thus, programmed cell death, or apoptosis …

[HTML][HTML] Chemopreventive effects of vitamin D3 and its analogue, paricalcitol, in combination with 5-fluorouracil against colorectal cancer: The role of calcium …

A Aslam, J Ahmad, MA Baghdadi, S Idris… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Background Although vitamin D (VD) is chemoprotective and enhances 5-
fluorouracil (5-FU) cytotoxicity against colorectal cancer (CRC), little is known about its …

Vitamin D: Can gender medicine have a role?

T Ciarambino, P Crispino, G Minervini, M Giordano - Biomedicines, 2023 - mdpi.com
This narrative review aims to shed light on the role of gender differences, on the biological
and molecular functions in the main pathological mechanisms that recognize the role of …

Newly-identified pathways relating vitamin D to carcinogenesis: a review

N Bilani, L Elson, C Szuchan, E Elimimian, M Saleh… - in vivo, 2021 - iv.iiarjournals.org
Background: The epidemiological relationship between vitamin D levels and cancer has
been thoroughly investigated. Published data from large studies appear to corroborate a …