Skeletal muscle glucose uptake during exercise: how is it regulated?

AJ Rose, EA Richter - Physiology, 2005 - journals.physiology.org
The increase in skeletal muscle glucose uptake during exercise results from a coordinated
increase in rates of glucose delivery (higher capillary perfusion), surface membrane glucose …

Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle

A Zorzano, M Palacin, A Guma - Acta Physiologica …, 2005 - Wiley Online Library
Skeletal muscle is a major glucose‐utilizing tissue in the absorptive state and the major
glucose transporter expressed in muscle in adulthood is GLUT4. GLUT4 expression is …

The Charcot–Marie–Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system

S Pich, D Bach, P Briones, M Liesa… - Human molecular …, 2005 - academic.oup.com
Abstract Mitofusin-2 (Mfn2) is a mitochondrial membrane protein that participates in
mitochondrial fusion in mammalian cells and mutations in the Mfn2 gene cause Charcot …

[HTML][HTML] Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

Z Chen, GX Wang, SL Ma, DY Jung, H Ha… - Molecular …, 2017 - Elsevier
Objective Brown and white adipose tissue exerts pleiotropic effects on systemic energy
metabolism in part by releasing endocrine factors. Neuregulin 4 (Nrg4) was recently …

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

M Masin, J Vazquez, S Rossi, S Groeneveld… - Cancer & …, 2014 - Springer
Background Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT)
constitute two important characteristics of carcinoma progression toward invasive cancer …

Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease

A Geissler, S Ryzhov, DB Sawyer - Clinical Science, 2020 - portlandpress.com
Neuregulins (NRGs) are protein ligands that act through ErbB receptor tyrosine kinases to
regulate tissue morphogenesis, plasticity, and adaptive responses to physiologic needs in …

Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1β/erbB4 signaling

Y Kuramochi, GM Cote, X Guo, NK Lebrasseur… - Journal of Biological …, 2004 - ASBMB
Neuregulin (NRG)-1β has a prosurvival effect on cardiac myocytes via the
phosphatidylinositol-3-kinase/Akt pathway, but the physiological regulators of this system in …

μ and κ opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes

MM Belcheva, AL Clark, PD Haas, JS Serna… - Journal of Biological …, 2005 - ASBMB
Acute μ and κ opioids activate the ERK/MAPK phosphorylation cascade that represents an
integral part of the signaling pathway of growth factors in astrocytes. By this cross-talk …

[HTML][HTML] The cardiotoxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine

X Peng, B Chen, CC Lim… - Molecular …, 2005 - triggered.stanford.clockss.org
Anthracyclines remain a mainstay of chemotherapy in spite of their well-recognized
cardiotoxicity. Recent experience with trastuzumab (Herceptin) and anthracycline therapy …

Epigallocatechin gallate induces GLUT4 translocation in skeletal muscle through both PI3K-and AMPK-dependent pathways

M Ueda-Wakagi, K Hayashibara, T Nagano, M Ikeda… - Food & function, 2018 - pubs.rsc.org
Our previous report demonstrated that epigallocatechin gallate (EGCg) promotes
translocation of glucose transporter 4 (GLUT4) in skeletal muscle. In this study, we …