Microvascular endothelial cells in the kidney have been a neglected cell type in sepsis-
induced acute kidney injury (sepsis-AKI) research; yet, they offer tremendous potential as …

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted …

An essential step in renal function entails the formation of an ultrafiltrate that is delivered to
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …

Evidence accumulating over the last decade has established the fundamental role of
vascular endothelial growth factor (VEGF) as a key regulator of normal and abnormal …

TGF-β (transforming growth factor-β) and BMP-7 (bone morphogenetic protein-7), two key
members in the TGF-β superfamily, play important but diverse roles in CKDs (chronic kidney …

Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …

Since discovery over a decade ago of a role for the cytokine TGF-ß as key mediator of
glomerular and tubulointerstitial pathobiology in chronic kidney diseases, studies of TGF-ß …

Role of vascular endothelial growth factor in the regulation of angiogenesis. Compelling
evidence indicates that vascular endothelial growth factor (VEGF) is a fundamental regulator …

Recent clinical and animal studies have shown that acute kidney injury (AKI), even if
followed by complete recovery of renal function, can eventually result in chronic kidney …

The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Vascular
endothelial growth factor (VEGF) is an endothelial-specific growth factor that promotes …