Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …

Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …

Less than half of human zygotes survive to birth, primarily due to aneuploidies of meiotic or
mitotic origin. Mitotic errors generate chromosomal mosaicism, defined by multiple cell …

Purpose Azoospermia affects 1% of men and it can be the consequence of spermatogenic
maturation arrest (MA). Although the etiology of MA is likely to be of genetic origin, only 13 …

Successful human reproduction requires gamete maturation, fertilization, and early
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …

BACKGROUND Meiosis is an essential stage in the life cycle of sexually reproducing
species, underlying formation of haploid gametes and serving as the basis of genetic …

It is estimated that one in 100 men have azoospermia, the complete lack of sperm in the
ejaculate. Currently,~ 20% of azoospermia cases remain idiopathic. Non-obstructive …

BACKGROUND Our genetic code is now readable, writable and hackable. The recent
escalation of genome-wide sequencing (GS) applications in population diagnostics will not …