Macrophage activation syndrome in adults: recent advances in pathophysiology, diagnosis and treatment
Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome, which if not
promptly treated, can lead rapidly to critical illness and death. HLH is termed macrophage …
promptly treated, can lead rapidly to critical illness and death. HLH is termed macrophage …
Diagnosis and management of secondary HLH/MAS following HSCT and CAR-T cell therapy in adults; a review of the literature and a survey of practice within EBMT …
RD Sandler, RS Tattersall, H Schoemans… - Frontiers in …, 2020 - frontiersin.org
Introduction: Secondary haemophagocytic lymphohistiocytosis (sHLH) or Macrophage
Activation Syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur …
Activation Syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur …
The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage …
B Shakoory, A Geerlinks, M Wilejto, K Kernan… - Annals of the rheumatic …, 2023 - Elsevier
Objective Haemophagocytic lymphohistiocytosis (HLH) and macrophage activation
syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can …
syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can …
An improved index for diagnosis and mortality prediction in malignancy-associated hemophagocytic lymphohistiocytosis
A Zoref-Lorenz, J Murakami, L Hofstetter… - Blood, The Journal …, 2022 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening inflammatory syndrome that
may complicate hematologic malignancies (HMs). The appropriateness of current criteria for …
may complicate hematologic malignancies (HMs). The appropriateness of current criteria for …
A consensus review on malignancy‐associated hemophagocytic lymphohistiocytosis in adults
N Daver, K McClain, CE Allen, SA Parikh, Z Otrock… - Cancer, 2017 - Wiley Online Library
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of severe immune activation and
dysregulation resulting in extreme and often life‐threatening inflammation. HLH has been …
dysregulation resulting in extreme and often life‐threatening inflammation. HLH has been …
Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry
S Birndt, T Schenk, B Heinevetter… - Journal of cancer …, 2020 - Springer
Purpose Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory
syndrome emerging from a deregulated immune response due to various triggers. In adults …
syndrome emerging from a deregulated immune response due to various triggers. In adults …
Performances of the H-score for diagnosis of hemophagocytic lymphohistiocytosis in adult and pediatric patients
F Debaugnies, B Mahadeb, A Ferster… - American journal of …, 2016 - academic.oup.com
Objectives: In this study, we compared the performances of adapted hemophagocytic
lymphohistiocytosis (HLH)–2004 guidelines with those of the new diagnostic H-score to …
lymphohistiocytosis (HLH)–2004 guidelines with those of the new diagnostic H-score to …
Recommendations for the use of etoposide-based therapy and bone marrow transplantation for the treatment of HLH: consensus statements by the HLH Steering …
S Ehl, I Astigarraga, T von Bahr Greenwood… - The Journal of Allergy …, 2018 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory
syndrome requiring aggressive immunosuppressive therapy. Following 2 large international …
syndrome requiring aggressive immunosuppressive therapy. Following 2 large international …
Advances in the pathogenesis of primary and secondary haemophagocytic lymphohistiocytosis: differences and similarities
E Brisse, CH Wouters, P Matthys - British Journal of …, 2016 - Wiley Online Library
Haemophagocytic lymphohistiocytosis (HLH) comprises a heterogeneous spectrum of
hyperinflammatory conditions that are inherited (primary HLH) or acquired in a context of …
hyperinflammatory conditions that are inherited (primary HLH) or acquired in a context of …
[HTML][HTML] Current status of the diagnosis and treatment of hemophagocytic lymphohistiocytosis in adults
YR Kim, DY Kim - Blood research, 2021 - synapse.koreamed.org
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a
disruption of the regulatory pathway that terminates immune and inflammatory responses …
disruption of the regulatory pathway that terminates immune and inflammatory responses …