Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

A Idnurm, YS Bahn, K Nielsen, X Lin… - Nature Reviews …, 2005 - nature.com
Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi

JH Yu, Z Hamari, KH Han, JA Seo… - Fungal genetics and …, 2004 - Elsevier
Gene replacement via homologous double crossover in filamentous fungi requires relatively
long (preferentially> 0.5 kb) flanking regions of the target gene. For this reason, gene …

[图书][B] Cryptococcus neoformans

A Casadevall, JR Perfect - 1998 - Citeseer
MATERIALS AND METHODS Strains and media. C. neoformans var. grubii strains H99 (70),
KN99a (55), KN99 (55), KN99aNAT, and KN99NAT were maintained at 80 C. Cultures were …

Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen Candida albicans

SM Noble, AD Johnson - Eukaryotic cell, 2005 - Am Soc Microbiol
Candida albicans is the most common human fungal pathogen and causes significant
morbidity and mortality worldwide. Nevertheless, the basic principles of C. albicans …

Chitosan, the Deacetylated Form of Chitin, Is Necessary for Cell Wall Integrity in Cryptococcus neoformans

LG Baker, CA Specht, MJ Donlin, JK Lodge - Eukaryotic cell, 2007 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococcal
meningoencephalitis, particularly in immunocompromised patients. The fungal cell wall is an …

Sexual Cycle of Cryptococcus neoformans var. grubii and Virulence of Congenic a and α Isolates

K Nielsen, GM Cox, P Wang, DL Toffaletti… - Infection and …, 2003 - Am Soc Microbiol
Cryptococcus neoformans is a human-pathogenic fungus that has evolved into three distinct
varieties that infect most prominently the central nervous system. A sexual cycle involving …

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

KW Jung, DH Yang, S Maeng, KT Lee, YS So… - Nature …, 2015 - nature.com
Cryptococcus neoformans causes life-threatening meningoencephalitis in humans, but its
overall biological and pathogenic regulatory circuits remain elusive, particularly due to the …

Evidence that RNA silencing functions as an antiviral defense mechanism in fungi

GC Segers, X Zhang, F Deng… - Proceedings of the …, 2007 - National Acad Sciences
The role of RNA silencing as an antiviral defense mechanism in fungi was examined by
testing the effect of dicer gene disruptions on mycovirus infection of the chestnut blight …

Light controls growth and development via a conserved pathway in the fungal kingdom

A Idnurm, J Heitman - PLoS biology, 2005 - journals.plos.org
Light inhibits mating and haploid fruiting of the human fungal pathogen Cryptococcus
neoformans, but the mechanisms involved were unknown. Two genes controlling light …