Nuclear lamins: laminopathies and their role in premature ageing
It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …
Organoid systems to study the human female reproductive tract and pregnancy
Both the proper functioning of the female reproductive tract (FRT) and normal placental
development are essential for women's health, wellbeing, and pregnancy outcome. The …
development are essential for women's health, wellbeing, and pregnancy outcome. The …
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.
A Schermer, S Galvin, TT Sun - The Journal of cell biology, 1986 - rupress.org
In this paper we present keratin expression data that lend strong support to a model of
corneal epithelial maturation in which the stem cells are located in the limbus, the …
corneal epithelial maturation in which the stem cells are located in the limbus, the …
Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.
R Moll, A Löwe, J Laufer, WW Franke - The American journal of …, 1992 - ncbi.nlm.nih.gov
The authors have recently identified a new cytokeratin (CK) polypeptide, CK 20, whose
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …
Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study
RA Röber, K Weber, M Osborn - Development, 1989 - journals.biologists.com
In mouse embryos, acquisition of the nuclear lamin polypeptides A/C varies according to
developmental stage and tissue type. In order to determine the precise time points and cell …
developmental stage and tissue type. In order to determine the precise time points and cell …
Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.
R Moll, DL Schiller, WW Franke - The Journal of cell biology, 1990 - rupress.org
A major cytoskeletal polypeptide (Mr approximately 46,000; protein IT) of human intestinal
epithelium was characterized by biochemical and immunological methods. The polypeptide …
epithelium was characterized by biochemical and immunological methods. The polypeptide …
Chaperone activity of alpha‐crystallins modulates intermediate filament assembly.
ID Nicholl, RA Quinlan - The EMBO journal, 1994 - embopress.org
Intermediate filaments are generally regarded as one of the most insoluble and resilient
cytoskeletal structures of eukaryotic cells. In extracts from the ocular lens, we noticed an …
cytoskeletal structures of eukaryotic cells. In extracts from the ocular lens, we noticed an …
Antibody markers of basal cells in complex epithelia
PE Purkis, JB Steel, IC Mackenzie… - Journal of cell …, 1990 - journals.biologists.com
In the course of immunohistochemical studies it has become apparent that there is a distinct
phenotype of keratin expression that is shared by basal epithelial cells in a variety of …
phenotype of keratin expression that is shared by basal epithelial cells in a variety of …
Functional mapping and single chain construction of the anti-cytokeratin 8 monoclonal antibody TS1
The anti-cytokeratin (CK) 8 monoclonal antibody (mab) TS1 has been shown to efficiently
bind to CK8 expressed in carcinomas in vivo. The anti-idiotypic antibody of TS1, αTS1, can …
bind to CK8 expressed in carcinomas in vivo. The anti-idiotypic antibody of TS1, αTS1, can …
Acidic and basic hair/nail (" hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to" soft" keratins.
MH Lynch, WM O'Guin, C Hardy, L Mak… - The Journal of cell …, 1986 - rupress.org
Although numerous hair proteins have been studied biochemically and many have been
sequenced, relatively little is known about their in situ distribution and differential expression …
sequenced, relatively little is known about their in situ distribution and differential expression …