Nuclear lamins: laminopathies and their role in premature ageing

JLV Broers, FCS Ramaekers, G Bonne… - Physiological …, 2006 - journals.physiology.org
It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …

Organoid systems to study the human female reproductive tract and pregnancy

L Alzamil, K Nikolakopoulou, MY Turco - Cell Death & Differentiation, 2021 - nature.com
Both the proper functioning of the female reproductive tract (FRT) and normal placental
development are essential for women's health, wellbeing, and pregnancy outcome. The …

Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.

A Schermer, S Galvin, TT Sun - The Journal of cell biology, 1986 - rupress.org
In this paper we present keratin expression data that lend strong support to a model of
corneal epithelial maturation in which the stem cells are located in the limbus, the …

Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.

R Moll, A Löwe, J Laufer, WW Franke - The American journal of …, 1992 - ncbi.nlm.nih.gov
The authors have recently identified a new cytokeratin (CK) polypeptide, CK 20, whose
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …

Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study

RA Röber, K Weber, M Osborn - Development, 1989 - journals.biologists.com
In mouse embryos, acquisition of the nuclear lamin polypeptides A/C varies according to
developmental stage and tissue type. In order to determine the precise time points and cell …

Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.

R Moll, DL Schiller, WW Franke - The Journal of cell biology, 1990 - rupress.org
A major cytoskeletal polypeptide (Mr approximately 46,000; protein IT) of human intestinal
epithelium was characterized by biochemical and immunological methods. The polypeptide …

Chaperone activity of alpha‐crystallins modulates intermediate filament assembly.

ID Nicholl, RA Quinlan - The EMBO journal, 1994 - embopress.org
Intermediate filaments are generally regarded as one of the most insoluble and resilient
cytoskeletal structures of eukaryotic cells. In extracts from the ocular lens, we noticed an …

Antibody markers of basal cells in complex epithelia

PE Purkis, JB Steel, IC Mackenzie… - Journal of cell …, 1990 - journals.biologists.com
In the course of immunohistochemical studies it has become apparent that there is a distinct
phenotype of keratin expression that is shared by basal epithelial cells in a variety of …

Functional mapping and single chain construction of the anti-cytokeratin 8 monoclonal antibody TS1

P Holm, R Jafari, BE Sundström - Molecular Immunology, 2007 - Elsevier
The anti-cytokeratin (CK) 8 monoclonal antibody (mab) TS1 has been shown to efficiently
bind to CK8 expressed in carcinomas in vivo. The anti-idiotypic antibody of TS1, αTS1, can …

Acidic and basic hair/nail (" hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to" soft" keratins.

MH Lynch, WM O'Guin, C Hardy, L Mak… - The Journal of cell …, 1986 - rupress.org
Although numerous hair proteins have been studied biochemically and many have been
sequenced, relatively little is known about their in situ distribution and differential expression …