G-protein-coupled receptors (GPCRs) are known to play central roles in the physiology of
many organisms. Members of this seven α-helical transmembrane protein family transduce …

Ticks are blood-feeding arthropods that require heme for their successful reproduction.
During feeding they also acquire pathogens that are subsequently transmitted to humans …

In arthropods, eicosanoids derived from the oxygenated metabolism of arachidonic acid are
significant in mediating immune responses. However, the lack of information about insect …

The cattle fever tick, Rhipicephalus microplus (Canestrini)(Acari: Ixodidae), is a one-host tick
that infests primarily cattle in tropical and sub-tropical regions of the world. This species …

BACKGROUND Kinins are multifunctional neuropeptides that regulate key insect
physiological processes such as diuresis, feeding, and ecdysis. However, the physiological …

BACKGROUND The southern cattle tick, Rhipicephalus microplus, is a primary vector of the
deadly bovine disease babesiosis. Worldwide populations of ticks have developed …

Pyrokinins (PKs) are pleiotropic neuropeptides with significant roles in invertebrate
physiology. Although functions of PKs are known in insects, there is a lack of knowledge of …

The causative agent for Chagas disease, Trypanosoma cruzi, is transmitted to a human host
in the urine/feces of the kissing bug, Rhodnius prolixus, following blood feeding. Kinins are …

BACKGROUND The discovery of ecofriendly insecticides through a new strategy for aphid
control is important because of the substantial resistance and unexpected eco‐toxicity to …

The success of the acaricide amitraz, a ligand of the tick tyramine/octopamine receptor (a G
protein-coupled receptor; GPCR), stimulated interest on arthropod-specific GPCRs as …