Form follows function: nanoparticle shape and its implications for nanomedicine
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …
understanding how the geometry and size of nanoparticles affect their interaction with …
Physical principles of nanoparticle cellular endocytosis
This review article focuses on the physiochemical mechanisms underlying nanoparticle
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
Entry of nanoparticles into cells: The importance of nanoparticle properties
J Zhao, MH Stenzel - Polymer Chemistry, 2018 - pubs.rsc.org
Knowledge of the interactions between nanoparticles (NPs) and cell membranes is of great
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …
Rethinking CRITID procedure of brain targeting drug delivery: circulation, blood brain barrier recognition, intracellular transport, diseased cell targeting, internalization …
The past decades have witnessed great progress in nanoparticle (NP)‐based brain‐
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …
Cellular uptake of nanoparticles as determined by particle properties, experimental conditions, and cell type
K Kettler, K Veltman, D van De Meent… - Environmental …, 2014 - Wiley Online Library
The increased application of nanoparticles (NPs) is increasing the risk of their release into
the environment. Although many toxicity studies have been conducted, the environmental …
the environment. Although many toxicity studies have been conducted, the environmental …
Ligand density on nanoparticles: A parameter with critical impact on nanomedicine
Nanoparticles modified with ligands for specific targeting towards receptors expressed on
the surface of target cells are discussed in literature towards improved delivery strategies. In …
the surface of target cells are discussed in literature towards improved delivery strategies. In …
Understanding cellular interactions with nanomaterials: Towards a rational design of medical nanodevices
F Villanueva-Flores, A Castro-Lugo, OT Ramírez… - …, 2020 - iopscience.iop.org
Biomedical applications increasingly require fully characterized new nanomaterials. There is
strong evidence showing that nanomaterials not only interact with cells passively but also …
strong evidence showing that nanomaterials not only interact with cells passively but also …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Effect of micro-and nanoparticle shape on biological processes
H Hadji, K Bouchemal - Journal of Controlled Release, 2022 - Elsevier
In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …
Physiologically based pharmacokinetic modeling of nanoparticles
M Li, KT Al-Jamal, K Kostarelos, J Reineke - ACS nano, 2010 - ACS Publications
Rapid expansion of nanoparticle research demands new technologies that will enable better
interpretation of experimental data and assistance in the rational design of future …
interpretation of experimental data and assistance in the rational design of future …