Muscular weakness and muscle wasting in the critically ill

JC Schefold, T Wollersheim, JJ Grunow… - Journal of cachexia …, 2020 - Wiley Online Library
Background Muscular weakness and/or muscle wasting is recognized as a key medical
problem in critically ill patients on intensive care units (ICUs) worldwide. Methods and …

The sick and the weak: neuropathies/myopathies in the critically ill

O Friedrich, MB Reid, G Van den Berghe… - Physiological …, 2015 - journals.physiology.org
Critical illness polyneuropathies (CIP) and myopathies (CIM) are common complications of
critical illness. Several weakness syndromes are summarized under the term intensive care …

A framework for diagnosing and classifying intensive care unit-acquired weakness

RD Stevens, SA Marshall, DR Cornblath… - Critical care …, 2009 - journals.lww.com
Neuromuscular dysfunction is prevalent in critically ill patients, is associated with worse
short-term outcomes, and is a determinant of long-term disability in intensive care unit …

Acute myopathy of intensive care: clinical, electromyographic, and pathological aspects

D Lacomis, MJ Giuliani, A van Cott… - Annals of Neurology …, 1996 - Wiley Online Library
An acute myopathy of intensive care occurs in critically ill patients treated with intravenous
corticosteroids and neuromuscular junction‐blocking agents. The full clinicopathological …

Causes of neuromuscular weakness in the intensive care unit: a study of ninety‐two patients

D Lacomis, JT Petrella… - Muscle & Nerve: Official …, 1998 - Wiley Online Library
The spectrum of neuromuscular disorders among intensive care unit (ICU) patients has
shifted toward disorders acquired within the ICU and away from “traditional” neuromuscular …

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

S Weber-Carstens, J Schneider… - American journal of …, 2013 - atsjournals.org
Rationale: Critical illness myopathy (CIM) has no known cause and no treatment.
Immobilization and impaired glucose metabolism are implicated. Objectives: We assessed …

[HTML][HTML] Chronic muscle weakness and mitochondrial dysfunction in the absence of sustained atrophy in a preclinical sepsis model

AM Owen, SP Patel, JD Smith, BK Balasuriya, SF Mori… - Elife, 2019 - elifesciences.org
Chronic critical illness is a global clinical issue affecting millions of sepsis survivors
annually. Survivors report chronic skeletal muscle weakness and development of new …

Proxy-bridged image reconstruction network for anomaly detection in medical images

K Zhou, J Li, W Luo, Z Li, J Yang, H Fu… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Anomaly detection in medical images refers to the identification of abnormal images with
only normal images in the training set. Most existing methods solve this problem with a self …

Acute myopathy after liver transplantation

JV Campellone, D Lacomis, DJ Kramer, AC Van Cott… - Neurology, 1998 - AAN Enterprises
Acute myopathy is a cause of weakness and additional morbidity in a variety of critically ill
patients, including transplant recipients. We report the incidence of and risk factors …

Muscle toxicity of drugs: when drugs turn physiology into pathophysiology

L Janssen, NAE Allard, CGJ Saris… - Physiological …, 2020 - journals.physiology.org
Drugs are prescribed to manage or prevent symptoms and diseases, but may sometimes
cause unexpected toxicity to muscles. The symptomatology and clinical manifestations of the …