Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Rationale Disorders of compulsivity such as stimulant use disorder (SUD) and obsessive-
compulsive disorder (OCD) are characterised by deficits in behavioural flexibility, some of …

Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a
potential transdiagnostic symptom of several neuropsychiatric disorders, including …

Deer mice (Peromyscus maniculatus bairdii), a wildtype species native to North America,
have been investigated for their spontaneous compulsive-like behaviour. The repetitive and …

Identifying vulnerable individuals before they transition to a compulsive pattern of drug
seeking and taking is a key challenge in addiction to develop efficient prevention strategies …

Abstract Obsessive Compulsive Disorder (OCD) is a severe, chronic, and highly prevalent
psychiatric disorder that affects between 1.5% and 3% of people worldwide. Despite its …

Obsessive-compulsive disorder (OCD) is a disabling mental condition that poses recurring
bothersome intrusive thoughts, obsessions, and compulsions. Considering the positive …

Obsessive-compulsive disorder (OCD) is a relatively common neuropsychiatric disorder
affecting between 1.6 and 3.2% of the population. A number of studies have previously …

The monoamine oxidases (MAOA/B) and catechol-O-methyltransferase (COMT) enzymes
break down regulatory components within serotonin and dopamine pathways, and …