Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Luminescent metal nanoclusters: Biosensing strategies and bioimaging applications

Y Xiao, Z Wu, Q Yao, J Xie - Aggregate, 2021 - Wiley Online Library
Metal nanoclusters (MNCs) are ultrasmall metal‐organic aggregates, composed of a metal
core less than 2 nm and a protecting shell of metal‐organic ligand motifs. The controlled …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Metal nanoclusters: novel probes for diagnostic and therapeutic applications

Y Tao, M Li, J Ren, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal nanoclusters, composed of several to a few hundred metal atoms, have received
worldwide attention due to their extraordinary physical and chemical characteristics …

Gold nanoclusters for theranostic applications

Y Zheng, J Wu, H Jiang, X Wang - Coordination Chemistry Reviews, 2021 - Elsevier
Gold nanoclusters, consisting of a few to several hundred Au atoms with a core size below 2
nm, have attracted worldwide attention in the biomedicine because of their supernormal …

Metal nanoclusters: new fluorescent probes for sensors and bioimaging

L Zhang, E Wang - Nano Today, 2014 - Elsevier
Fluorescent metal nanoclusters (NCs) as a new class of fluorophores have attracted more
and more attention due to their unique electronic structures and the subsequent unusual …

[HTML][HTML] Aptamer binding assays for proteins: the thrombin example—a review

B Deng, Y Lin, C Wang, F Li, Z Wang, H Zhang… - Analytica chimica …, 2014 - Elsevier
Experimentally selected single-stranded DNA and RNA aptamers are able to bind to specific
target molecules with high affinity and specificity. Many analytical methods make use of …

Nanotechnology-Enhanced No-Wash Biosensors for in Vitro Diagnostics of Cancer

X Huang, Y Liu, B Yung, Y Xiong, X Chen - ACS nano, 2017 - ACS Publications
In vitro biosensors have been an integral component for early diagnosis of cancer in the
clinic. Among them, no-wash biosensors, which only depend on the simple mixing of the …

DNA-mediated homogeneous binding assays for nucleic acids and proteins

H Zhang, F Li, B Dever, XF Li, XC Le - Chemical reviews, 2013 - ACS Publications
The detection of nucleic acids and proteins is fundamental for studying their functions and
for the development of molecular diagnostics. These molecules carry out most biological …

DNA metallization: principles, methods, structures, and applications

Z Chen, C Liu, F Cao, J Ren, X Qu - Chemical Society Reviews, 2018 - pubs.rsc.org
DNA metallization has witnessed tremendous growth and development, from the initial
simple synthesis aimed at manufacturing conductive metal nanowires to the current …