Synthesis, molecular docking and anti-inflammatory evaluation of new trisubstituted pyrazoline derivatives bearing benzenesulfonamide moiety
A new series of trisubstituted pyrazoline bearing benzenesulfonamide moiety 6a, b–10a, b
were designed, synthesised and evaluated for their anti-inflammatory in vitro. Before starting …
were designed, synthesised and evaluated for their anti-inflammatory in vitro. Before starting …
Synthesis of new polymers linked to heterocyclic using zinc oxide with nanostructures extracted from natural sources
KA Thejeel, SAAS Abdul Kareem… - Egyptian Journal of …, 2022 - ejchem.journals.ekb.eg
This research has been directed towards the polymerization of heterocyclic compounds by
reaction it with acrylic acid to prepare new polymeric compounds using zinc oxide …
reaction it with acrylic acid to prepare new polymeric compounds using zinc oxide …
Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening
JA Baptista, MTS Rosado, RAE Castro, AOL Évora… - Molecules, 2021 - mdpi.com
In this work, co-crystal screening was carried out for two important dihydrofolate reductase
(DHFR) inhibitors, trimethoprim (TMP) and pyrimethamine (PMA), and for 2, 4 …
(DHFR) inhibitors, trimethoprim (TMP) and pyrimethamine (PMA), and for 2, 4 …
Synthesis and antibacterial evaluation of new2‐phenylbenzimidazole derivatives
Bacterial DNA gyrase and topoisomerase IV are well‐characterized targets for both
fluoroquinolones (eg Ciprofloxacin), which inhibit the catalytic subunits GyrA/ParC, and …
fluoroquinolones (eg Ciprofloxacin), which inhibit the catalytic subunits GyrA/ParC, and …
Design, Synthesis, and Antibacterial, Antifungal, and Antioxidant Activities of New Four Membered Rings from Derivatives Containing a 4(3H)-Quinazolinone Moiety …
NN Saeed, SMH Al-Majidi - Russian Journal of Bioorganic Chemistry, 2024 - Springer
Objective: The aim of this study is to produce novel 4 (3 H)-quinazolinone derivatives,
analyze their efficacy as antibacterial and antifungal agents, and investigate their antioxidant …
analyze their efficacy as antibacterial and antifungal agents, and investigate their antioxidant …
Synthesis, Biological Evaluation, Molecular Docking, and Molecular Dynamic Simulation Studies of Some New 5-(3, 4, 5-Trimethoxybenzyl) pyrimidine-2, 4-diamine …
Pavithra, I Pushpavathi, KMM Pasha… - Russian Journal of …, 2024 - Springer
Objective: This article is focused on synthesis and characterisation of 1, 1-(((5-(3, 4,
5triethoxybenzyl) pyrimidine-2, 4-diyl)) bis (azanediyl)) bis (substituted phenyl methylene)) …
5triethoxybenzyl) pyrimidine-2, 4-diyl)) bis (azanediyl)) bis (substituted phenyl methylene)) …
Synthesis, identification and evaluation of molecular docking and experimental anti-cancer and antioxidant activity of new spiro four membered ring derivatives …
HAM Rasheed, SMH Al-Majidi - Natural Product Research, 2024 - Taylor & Francis
Abstract Spiro-5-nitro isatino aza-β-lactams were produced by a [2+ 2] cycloaddition of 5-
nitro isatin Schiff bases [1–5] with different aromatic isocyanate and thioisocyanate. 1HNMR …
nitro isatin Schiff bases [1–5] with different aromatic isocyanate and thioisocyanate. 1HNMR …
[HTML][HTML] Успехи химии гетероциклических азидов
ВА Бакулев, ЮМ Шафран, НА Беляев… - Russian Chemical …, 2022 - uspkhim.ru
Аннотация В настоящем обзоре впервые систематизированы особенности синтеза и
реакций гетероциклических азидов с производными ацетилена и ацетонитрила …
реакций гетероциклических азидов с производными ацетилена и ацетонитрила …