The coordination modes of (thio) semicarbazone copper (II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity
Thiosemicarbazones are promising candidates for anticancer therapy and their mechanism
of action is often linked to their metal chelating ability. In this study, five (thio) …
of action is often linked to their metal chelating ability. In this study, five (thio) …
Triapine analogues and their copper (II) complexes: Synthesis, characterization, solution speciation, redox activity, cytotoxicity, and mR2 RNR inhibition
I Besleaga, I Stepanenko, TV Petrasheuskaya… - Inorganic …, 2021 - ACS Publications
Three new thiosemicarbazones (TSCs) HL 1–HL 3 as triapine analogues bearing a redox-
active phenolic moiety at the terminal nitrogen atom were prepared. Reactions of HL 1–HL 3 …
active phenolic moiety at the terminal nitrogen atom were prepared. Reactions of HL 1–HL 3 …
Synthesis, X-ray and antibacterial activity of new copper (II) thiosemicarbazone complexes derived from 4-formyl-3-hydroxy-2-naphthoic acid
N Terenti, A Lazarescu, S Shova, P Bourosh… - Inorganica Chimica …, 2024 - Elsevier
New thiosemicarbazone ligand derived from 4-formyl-3-hydroxy-2-naphthoic acid (H 3 L· CH
3 OH (1)) and their two copper (II) complexes with composition [Cu (H 2 L) Cl] 2. 2 …
3 OH (1)) and their two copper (II) complexes with composition [Cu (H 2 L) Cl] 2. 2 …
[HTML][HTML] Regioselective synthesis, physicochemical properties and anticancer activity of 2-aminomethylated estrone derivatives
B Molnár, NI Kinyua, G Mótyán, P Leits, I Zupkó… - The Journal of Steroid …, 2022 - Elsevier
The unique estrogen receptor (ER)-independent antiproliferative and apoptotic activity of 2-
methoxyestradiol (2ME2) is well known, however, its use has been limited because of its …
methoxyestradiol (2ME2) is well known, however, its use has been limited because of its …
Complex formation of an estrone-salicylaldehyde semicarbazone hybrid with copper (II) and gallium (III): Solution equilibria and biological activity
The solution chemical properties such as proton dissociation, complex formation with copper
(II) and gallium (III) ions in addition to antibacterial and antitumor activity of a novel tridentate …
(II) and gallium (III) ions in addition to antibacterial and antitumor activity of a novel tridentate …
Estradiol-based salicylaldehyde (thio) semicarbazones and their copper complexes with anticancer, antibacterial and antioxidant activities
TV Petrasheuskaya, F Kovács, N Igaz, A Rónavári… - Molecules, 2022 - mdpi.com
A series of novel estradiol-based salicylaldehyde (thio) semicarbazones ((T) SCs) bearing
(O, N, S) and (O, N, O) donor sets and their Cu (II) complexes were developed and …
(O, N, S) and (O, N, O) donor sets and their Cu (II) complexes were developed and …
Novel Thiosemicarbazone Derivatives from Furan‐2‐Carbaldehyde: Synthesis, Characterization, Crystal Structures, and Antibacterial, Antifungal, Antioxidant, and …
W Hernández, F Carrasco, A Vaisberg… - Journal of …, 2023 - Wiley Online Library
Ten new thiosemicarbazone derivatives, furan‐2‐carbaldehyde thiosemicarbazone (1), 3‐
methyl‐furan‐2‐carbaldehyde thiosemicarbazone (2), 5‐hydroxymethyl‐furan‐2 …
methyl‐furan‐2‐carbaldehyde thiosemicarbazone (2), 5‐hydroxymethyl‐furan‐2 …
Binding models of copper (II) thiosemicarbazone complexes with human serum albumin: a speciation study
Copper (II) complexes of thiosemicarbazones (TSCs) often exhibit anticancer properties,
and their pharmacokinetic behavior can be affected by their interaction with blood transport …
and their pharmacokinetic behavior can be affected by their interaction with blood transport …
Structural and theoretical investigations, Hirshfeld surface analysis and anti-SARS CoV-2 of nickel (II) coordination complex
S Kumar, M Choudhary - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
A nickel (II) Schiff base complex,[Ni (L)(DMF)](1), was synthesized by treating NiCl2. 6H2O
with an ONS-donor Schiff base ligand (H2L) derived from the condensation 3, 5 …
with an ONS-donor Schiff base ligand (H2L) derived from the condensation 3, 5 …
Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation
HM Fahmy, FM Abdel-Rahman, AA El-Sayed… - BMC chemistry, 2023 - Springer
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …