Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy

AM Angelidi, MJ Belanger, A Kokkinos… - Endocrine …, 2022 - academic.oup.com
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Prebiotic effects: metabolic and health benefits

M Roberfroid, GR Gibson, L Hoyles… - British Journal of …, 2010 - cambridge.org
The different compartments of the gastrointestinal tract are inhabited by populations of micro-
organisms. By far the most important predominant populations are in the colon where a true …

Mechanisms of obesity-induced hypertension

V Kotsis, S Stabouli, S Papakatsika, Z Rizos… - Hypertension …, 2010 - nature.com
The relationship between obesity and hypertension is well established both in children and
adults. The mechanisms through which obesity directly causes hypertension are still an area …

Possible anti-obesity therapeutics from nature–A review

JW Yun - Phytochemistry, 2010 - Elsevier
Obesity is associated with many diseases, particularly diabetes, hypertension, osteoarthritis,
and heart disease. The obesity incidence has increased at an alarming rate in recent years …

The role of the gut microbiota in energy metabolism and metabolic disease

PD Cani, NM Delzenne - Current pharmaceutical design, 2009 - ingentaconnect.com
Obesity is now classically characterized by a cluster of several metabolic disorders, and by a
low grade inflammation. The evidence that the gut microbiota composition can be different …

[图书][B] Inulin-type fructans: functional food ingredients

M Roberfroid - 2004 - taylorfrancis.com
Inulin and oligofructose are naturally occurring resistant carbohydrates that have a variety of
uses as functional food ingredients. In addition to their role as prebiotics that selectively …

Appetite-controlling endocrine systems in teleosts

I Rønnestad, AS Gomes, K Murashita… - Frontiers in …, 2017 - frontiersin.org
Mammalian studies have shaped our understanding of the endocrine control of appetite and
body weight in vertebrates and provided the basic vertebrate model that involves central …

Obesity: Current and potential pharmacotherapeutics and targets

V Narayanaswami, LP Dwoskin - Pharmacology & therapeutics, 2017 - Elsevier
Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

The emerging role of the endocannabinoid system in endocrine regulation and energy balance

U Pagotto, G Marsicano, D Cota, B Lutz… - Endocrine …, 2006 - academic.oup.com
During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

[HTML][HTML] Natural anti-obesity agents

GA Mohamed, SRM Ibrahim, ES Elkhayat… - Bulletin of faculty of …, 2014 - Elsevier
Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle, and environmental factors, which favors a chronic positive energy balance, and …