Neoantigens: promising targets for cancer therapy
Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …
Immune checkpoint inhibitors promising role in cancer therapy: Clinical evidence and immune-related adverse events
The advent of immune checkpoint inhibitors (ICIs) has led to noteworthy progressions in the
management of diverse cancer types, as evidenced by the pioneering “ipilimumab” …
management of diverse cancer types, as evidenced by the pioneering “ipilimumab” …
CTLA4-Linked autoimmunity in the pathogenesis of endometriosis and related infertility: a systematic review
M Mikuš, MŠ Goldštajn, I Brlečić, S Dumančić… - International journal of …, 2022 - mdpi.com
Several studies, although with conflicting results, have sought to determine the
concentration of soluble CTLA4 antigens in peripheral blood plasma and peritoneal fluid in …
concentration of soluble CTLA4 antigens in peripheral blood plasma and peritoneal fluid in …
Regulating the regulatory T cells as cell therapies in autoimmunity and cancer
H Hosseinalizadeh, F Rabiee, N Eghbalifard… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Tregs), possess a pivotal function in the maintenance of immune
homeostasis. The dysregulated activity of Tregs has been associated with the onset of …
homeostasis. The dysregulated activity of Tregs has been associated with the onset of …
Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials
KT Kleber, KR Iranpur, LM Perry, SM Cruz… - Frontiers in …, 2022 - frontiersin.org
The microbiome has clearly been established as a cutting-edge field in tumor immunology
and immunotherapy. Growing evidence supports the role of the microbiome in immune …
and immunotherapy. Growing evidence supports the role of the microbiome in immune …
The role, relevance and management of immune exhaustion in bovine infectious diseases
Immune exhaustion is a state of immune cell dysfunction that occurs most commonly
following chronic exposure to an antigen which persists after the immune response fails to …
following chronic exposure to an antigen which persists after the immune response fails to …
[HTML][HTML] Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy
P Li, Y Xie, J Wang, C Bao, J Duan, Y Liu, Q Luo, J Xu… - Bioactive Materials, 2024 - Elsevier
Cancer patients by immune checkpoint therapy have achieved long-term remission, with no
recurrence of clinical symptoms of cancer for many years. Nevertheless, more than half of …
recurrence of clinical symptoms of cancer for many years. Nevertheless, more than half of …
[HTML][HTML] Development of OX40 agonists for canine cancer immunotherapy
Recent breakthroughs in cancer immunotherapy have provided unprecedented clinical
benefits to human cancer patients. Cancer is also one of the most common causes of death …
benefits to human cancer patients. Cancer is also one of the most common causes of death …
Checkpoint Inhibitors in Dogs: Are We There Yet?
A Giuliano, PAB Pimentel, RS Horta - Cancers, 2024 - mdpi.com
Simple Summary Immune checkpoints are essential to the body's reaction to immunological
stimuli. The most studied immune checkpoint molecules are programmed death (PD-1) with …
stimuli. The most studied immune checkpoint molecules are programmed death (PD-1) with …
A review on camelid nanobodies with potential application in veterinary medicine
E Tohidi, M Ghaemi, MS Golvajouei - Veterinary Research …, 2024 - Springer
The single variable domains of camelid heavy-chain only antibodies, known as nanobodies,
have taken a long journey since their discovery in 1989 until the first nanobody-based drug's …
have taken a long journey since their discovery in 1989 until the first nanobody-based drug's …