Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …

The advent of immune checkpoint inhibitors (ICIs) has led to noteworthy progressions in the
management of diverse cancer types, as evidenced by the pioneering “ipilimumab” …

Several studies, although with conflicting results, have sought to determine the
concentration of soluble CTLA4 antigens in peripheral blood plasma and peritoneal fluid in …

Regulatory T cells (Tregs), possess a pivotal function in the maintenance of immune
homeostasis. The dysregulated activity of Tregs has been associated with the onset of …

The microbiome has clearly been established as a cutting-edge field in tumor immunology
and immunotherapy. Growing evidence supports the role of the microbiome in immune …

Immune exhaustion is a state of immune cell dysfunction that occurs most commonly
following chronic exposure to an antigen which persists after the immune response fails to …

Cancer patients by immune checkpoint therapy have achieved long-term remission, with no
recurrence of clinical symptoms of cancer for many years. Nevertheless, more than half of …

Recent breakthroughs in cancer immunotherapy have provided unprecedented clinical
benefits to human cancer patients. Cancer is also one of the most common causes of death …

Simple Summary Immune checkpoints are essential to the body's reaction to immunological
stimuli. The most studied immune checkpoint molecules are programmed death (PD-1) with …

The single variable domains of camelid heavy-chain only antibodies, known as nanobodies,
have taken a long journey since their discovery in 1989 until the first nanobody-based drug's …