The corneal wound healing response is typically initiated by injuries to the epithelium and/or
endothelium that may also involve the stroma. However, it can also be triggered by immune …

Abstract The TGF beta-1,-2 and-3 isoforms are transcribed from different genes but bind to
the same receptors and signal through the same canonical and non-canonical signal …

PURPOSE: To report the clinical results of small incision lenticule extraction to correct
refractive errors using a femtosecond laser to refine the femtosecond lenticule extraction …

Purpose: The corneal wound healing response is of particular relevance for refractive
surgical procedures since it is a major determinant of efficacy and safety. The purpose of this …

Myofibroblasts are alpha-smooth muscle actin (SMA)+ cells that have a critical role in the
corneal stromal response to infections, injuries, and surgeries, and which produce corneal …

Purpose: The purpose of this review was to provide detailed insights into the
pathophysiology of myofibroblast-mediated fibrosis (scarring or late haze) after corneal …

Important advances have led to a better understanding of the biology and pathobiology of
corneal myofibroblasts and their generation after surgery, injury, infection and disease …

The aim of this study was to investigate the relationship between the level of stromal surface
irregularity after photorefractive keratectomy (PRK) and myofibroblast generation along with …

Small incision lenticule extraction (SMILE) is a new paradigm for refractive surgery, and was
first performed by Sekundo and Blum in 2008. It uses only a femtosecond laser to carve out …

The advent of the excimer laser as an intrument for use in reshaping the corneal stroma was
a great step forward in refractive surgery. Laser energy can be delivered on the stromal …