Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Piper nigrum L. is considered the king of spices throughout the world due to its pungent
principle piperine. Peppercorn of Piper nigrum as a whole or its active components are used …

The anti-inflammatory effects of phytochemicals, bioactive components from plants having
health benefits, have been heavily investigated in the last several decades. However, the …

Piperine is the main compound present in black pepper, and is the carrier of its specific
pungent taste, which is responsible for centuries of human dietary utilization and worldwide …

In India, Ayurveda has made a major contribution to the drug discovery process with new
means of identifying active compounds. Recent advancement in bioavailability …

Aim: To investigate the effects of piperine, a major pungent alkaloid present in Piper nigrum
and Piper longum, on the tumor growth and metastasis of mouse 4T1 mammary carcinoma …

Piperine is a bioactive component of black pepper, Piper nigrum Linn, commonly used for
daily consumption and in traditional medicine. Here, the molecular mechanisms by which …

Among the different types of breast cancers, triple-negative breast cancers (TNBCs) are
highly aggressive, do not respond to conventional hormonal/human epidermal growth factor …

The emergence of cancer stem cell theory has profound implications for cancer
chemoprevention and therapy. Cancer stem cells give rise to the tumor bulk through …