A Brief Overview of the Toxic Sphingomyelinase Ds of Brown Recluse Spider Venom and Other Organisms and Simple Methods To Detect Production of Its Signature …
H Lachmayr, H Alfred Jr - Molecular Pharmacology, 2024 - Elsevier
ABSTRACT A special category of phospholipase D (PLD) in the venom of the brown recluse
spider (Loxosceles reclusa) and several other sicariid spiders accounts for the …
spider (Loxosceles reclusa) and several other sicariid spiders accounts for the …
Dissecting peripheral protein-membrane interfaces
Peripheral membrane proteins (PMPs) include a wide variety of proteins that have in
common to bind transiently to the chemically complex interfacial region of membranes …
common to bind transiently to the chemically complex interfacial region of membranes …
Loxosceles amazonica Brown Spider venom: Insights into enzymatic activities, immunorecognition, and novel phospholipase D isoforms
R Silva-Magalhães, AL Silva-Araújo, P Peres-Damásio… - Biochimie, 2024 - Elsevier
The Loxosceles genus represents one of the main arachnid genera of medical importance in
Brazil. Despite the gravity of Loxosceles-related accidents, just a handful of species are …
Brazil. Despite the gravity of Loxosceles-related accidents, just a handful of species are …
Phosphatidylcholine Cation—Tyrosine π Complexes: Motifs for Membrane Binding by a Bacterial Phospholipase C
MF Roberts, A Gershenson, N Reuter - Molecules, 2022 - mdpi.com
Phosphatidylinositol-specific phospholipase C (PI-PLC) enzymes are a virulence factor in
many Gram-positive organisms. The specific activity of the Bacillus thuringiensis PI-PLC is …
many Gram-positive organisms. The specific activity of the Bacillus thuringiensis PI-PLC is …
Model mechanism for lipid uptake by the human STARD2/PC-TP phosphatidylcholine transfer protein
R Talandashti, M Moqadam… - The Journal of Physical …, 2024 - ACS Publications
The human StAR-related lipid transfer domain protein 2 (STARD2), also known as
phosphatidylcholine (PC) transfer protein, is a single-domain lipid transfer protein thought to …
phosphatidylcholine (PC) transfer protein, is a single-domain lipid transfer protein thought to …
Subtranscriptome analysis of phospholipases D in Loxosceles venom glands: Confirmation of predominance, intra-species diversity, and description of novel isoforms
JL Theodoro, HC da Justa… - International Journal of …, 2024 - Elsevier
Spiders of Loxosceles genus, or Brown spiders produce a potent venom with minimal
volume and protein content. Among its toxins, phospholipases D (PLDs) are notable for …
volume and protein content. Among its toxins, phospholipases D (PLDs) are notable for …
Brown spider venom phospholipase-D activity upon different lipid substrates
D Chaves-Moreira, LH Gremski, FR de Moraes… - Toxins, 2023 - mdpi.com
Brown spider envenomation results in dermonecrosis, characterized by an intense
inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D …
inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D …
Protein salvage and repurposing in evolution: Phospholipase D toxins are stabilized by a remodeled scrap of a membrane association domain
MHJ Cordes, AK Sundman, HC Fox… - Protein …, 2023 - Wiley Online Library
The glycerophosphodiester phosphodiesterase (GDPD)‐like SMaseD/PLD domain family,
which includes phospholipase D (PLD) toxins in recluse spiders and actinobacteria, evolved …
which includes phospholipase D (PLD) toxins in recluse spiders and actinobacteria, evolved …