[HTML][HTML] Cynarin alleviates intervertebral disc degeneration via protecting nucleus pulposus cells from ferroptosis

P Zhang, K Rong, J Guo, L Cui, K Kong, C Zhao… - Biomedicine & …, 2023 - Elsevier
Intervertebral disc degeneration (IVDD) leads to a series of degenerative spine diseases.
Clinical treatment of IVDD is mainly surgery, lacking effective drugs to alleviate intervertebral …

[HTML][HTML] Chemical Profiling and Evaluation of Antioxidant Activity of Artichoke (Cynara cardunculus var. scolymus) Leaf By-Products' Extracts Obtained with Green …

V Masala, S Jokić, K Aladić, M Molnar, M Casula… - Molecules, 2024 - mdpi.com
This study aimed to determine the effectiveness of different green extraction techniques
(GETs) on targeted bioactive compounds from artichoke leaf by-products using deep …

[HTML][HTML] Chemical Profile and Biological Properties of Methanolic and Ethanolic Extracts from the Aerial Parts of Inula britannica L. Growing in Central Asia

AK Ibadullayeva, M Kasela, KK Kozhanova… - Molecules, 2024 - mdpi.com
The genus Inula has been used in folk medicine for centuries; however, the data concerning
Inula britannica L. are scarce. This study aimed at investigating the chemical composition of …

[HTML][HTML] Enhancing antimicrobial and antiviral properties of Cynara scolymus L. waste through enzymatic pretreatment and lactic fermentation

E Cioni, M Di Stasi, E Iacono, M Lai, P Quaranta… - Food Bioscience, 2024 - Elsevier
This study explores the potential of Cynara scolymus L.(artichoke) waste as bioactive
compounds resource with antimicrobial and antiviral properties. Three extracts were …

Cynarine Exhibits Antiproliferative Activity and Bcl-2-Mediated Apoptotic Cell Death in Breast Cancer Cells

B ÖZDEM, I YILDIRIM, A KILINÇLI ÇETİN… - Pharmaceutical …, 2024 - Springer
Cynarine is a biologically active compound that is a derivative of hydroxycinnamic acid and
can exhibit a structure–function relationship and therapeutic potential due to its bioactive …

[HTML][HTML] Effects of Cynara scolymus L. Bract Extract on Lipid Metabolism Disorders Through Modulation of HMG-CoA Reductase, Apo A-1, PCSK-9, p-AMPK, SREBP-2 …

I Mokhtari, AA Shahat, OM Noman, D Milenkovic… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Objectives: Hyperlipidemia is a major contributor to metabolic complications
and tissue damage, leading to conditions such as liver steatosis, atherosclerosis, and …

The Effectiveness of Ultrasound-Assisted Extraction on Antioxidative Properties of Bract Leaves of Globe Artichoke

D Akdoğan, A Peksel - European Journal of Biology, 2023 - dergipark.org.tr
Objective: The antioxidant-rich artichoke bracts leaves are a particularly waste of the food
industry. Thus, it would be possible to utilize a cheap and natural material, which is industrial …