[HTML][HTML] Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a review of clinical and MRI features, diagnosis, and management
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the
most recently defined inflammatory demyelinating disease of the central nervous system …
most recently defined inflammatory demyelinating disease of the central nervous system …
[HTML][HTML] Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis
N Borisow, M Mori, S Kuwabara, M Scheel… - Frontiers in …, 2018 - frontiersin.org
Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …
Sex differences in autoimmune disorders of the central nervous system
Stronger adaptive immune responses in females can be observed in different mammals,
resulting in better control of infections compared to males. However, this presumably …
resulting in better control of infections compared to males. However, this presumably …
Association of higher ocrelizumab exposure with reduced disability progression in multiple sclerosis
Background and Objectives Ocrelizumab improved clinical and MRI measures of disease
activity and progression in three phase 3 multiple sclerosis (MS) studies. Post hoc analyses …
activity and progression in three phase 3 multiple sclerosis (MS) studies. Post hoc analyses …
Autoantibodies against central nervous system antigens in a subset of B cell–dominant multiple sclerosis patients
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS), with characteristic inflammatory lesions and demyelination. The clinical benefit of cell …
(CNS), with characteristic inflammatory lesions and demyelination. The clinical benefit of cell …
[HTML][HTML] Antibody therapies in autoimmune encephalitis
I Smets, MJ Titulaer - Neurotherapeutics, 2022 - Springer
Autoimmune encephalitis (AE) comprises a heterogeneous group of disorders in which the
host immune system targets self-antigens expressed in the central nervous system. The …
host immune system targets self-antigens expressed in the central nervous system. The …
Safety and efficacy of rituximab in multiple sclerosis: a retrospective observational study
Objective. To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical
practice setting. Methods. Clinical data for all adult patients with multiple sclerosis (MS) …
practice setting. Methods. Clinical data for all adult patients with multiple sclerosis (MS) …
[HTML][HTML] Exit strategies in natalizumab-treated RRMS at high risk of progressive multifocal leukoencephalopathy: a multicentre comparison study
A Zanghì, A Gallo, C Avolio, R Capuano, M Lucchini… - …, 2021 - Springer
The main aim of the study is to evaluate the efficacy and safety profile of ocrelizumab (OCR),
rituximab (RTX), and cladribine (CLA), employed as natalizumab (NTZ) exit strategies in …
rituximab (RTX), and cladribine (CLA), employed as natalizumab (NTZ) exit strategies in …
Ocrelizumab depletes T-lymphocytes more than rituximab in multiple sclerosis
N Capasso, A Nozzolillo, G Scalia, R Lanzillo… - Multiple Sclerosis and …, 2021 - Elsevier
Background We aim to directly compare changes in lymphocyte subpopulations between
chimeric (rituximab) and humanised (ocrelizumab) anti-CD20 antibodies in multiple …
chimeric (rituximab) and humanised (ocrelizumab) anti-CD20 antibodies in multiple …
[HTML][HTML] Treatment and relapse prevention of typical and atypical optic neuritis
G Saitakis, BK Chwalisz - International Journal of Molecular Sciences, 2022 - mdpi.com
Optic neuritis (ON) is an inflammatory condition involving the optic nerve. Several important
typical and atypical ON variants are now recognized. Typical ON has a more favorable …
typical and atypical ON variants are now recognized. Typical ON has a more favorable …