This review presents current knowledge on the molecular biology of retinoblastoma (RB).
Retinoblastoma is an intraocular tumor with hereditary and sporadic forms. 8,000 new cases …

Melphalan is an efficient chemotherapeutic agent for retinoblastoma (RB) in clinical practice.
However, the problems of drug resistance and poor prognosis caused by long-term …

Dysregulation of the CXCL12/CXCR4 axis is implicated in autoimmune, inflammatory, and
oncogenic diseases, positioning CXCR4 as a pivotal therapeutic target. We evaluated …

Simple Summary Effective management of retinoblastoma (RB), a common childhood eye
cancer, requires accurate diagnosis and monitoring during therapy. In this study, the liquid …

Retinoblastoma, a pediatric ocular malignancy, presents significant challenges in
comprehending its molecular underpinnings and targeted therapeutic approaches. The …

Simple Summary Retinoblastoma (RB) is a malignant childhood eye cancer. In search for
new or adjuvant treatment options, the gastric inhibitory polypeptide receptor (GIPR) …

Retinoblastoma represents the most prevalent malignant neoplasm affecting the eyes in
childhood. The clear-cut origin of retinoblastoma has not yet been determined; however …

Background Retinoblastoma (RB) is a rare primary malignant tumor primarily affecting
children. Our study aims to compare the overall survival (OS) between pediatric and adult …

Effective management of retinoblastoma (RB), the most prevalent childhood eye cancer,
depends on reliable monitoring and diagnosis. A promising candidate in this context is the …

Germline predisposing pathogenic variants (GPVs) are present in approximately 8–10% of
children with all cancer types. Very rare tumours (VRTs) represent many different diseases …