Abstract Purpose of Review This review critiques the ability of CT-based methods to predict
incident hip and vertebral fractures. Recent Findings CT-based techniques with concurrent …

Abstract Purpose of Review There are now three anabolic agents available for the treatment
of postmenopausal women at high risk for fracture. The purpose of this review is to supply a …

The effects of anabolic medications (teriparatide [TPTD] and parathyroid hormone [PTH])
differ in patients who have received recent treatment with potent antiresorptives. This …

This review provides a critical analysis of currently available approaches to increase bone
mass, structure and strength through drug therapy and of possible direct intra-osseous …

Bone is in a continuous state of remodeling whereby old bone is absorbed and new bone is
formed in its place. During this process, new formations reinforce the bone in the direction of …

Romosozumab monoclonal antibody treatment works by binding sclerostin and causing
rapid stimulation of bone formation while decreasing bone resorption. The location and local …

Abstract Purpose of Review Cortical bone mapping (CBM) is a technique for measuring
localised skeletal changes from computed tomography (CT) images. It can provide …

Highlights•'Anti-resorptive'drugs inhibit osteoclast differentiation or function by diverse
mechanisms.•Bisphosphonates are still the major drugs used for osteoporosis and skeletal …

There is little information on the effects of combination therapy for osteoporosis at the tissue
level. Using quadruple tetracycline‐labeled bone biopsies, we have compared the bone …

The central and peripheral skeleton was characterised using imaging techniques during 104
weeks of teriparatide treatment. Teriparatide exerts differential effects on the central and the …