Proteome of the luminal surface of the blood–brain barrier

JJ Hill, AS Haqqani, DB Stanimirovic - Proteomes, 2021 - mdpi.com
Interrogation of the molecular makeup of the blood–brain barrier (BBB) using proteomic
techniques has contributed to the cataloguing and functional understanding of the proteins …

Field evaluation of TaqMan Array Card (TAC) for the simultaneous detection of multiple respiratory viruses in children with acute respiratory infection

GA Weinberg, KC Schnabel, DD Erdman… - Journal of clinical …, 2013 - Elsevier
BACKGROUND: Multipathogen reverse transcription real-time PCR (RT-qPCR) platforms
have proven useful in surveillance for acute respiratory illness (ARI) and study of respiratory …

In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

Y Wang, N Wang, B Cai, G Wang, J Li… - Neural regeneration …, 2015 - journals.lww.com
Drugs for the treatment and prevention of nervous system diseases must permeate the blood-
brain barrier to take effect. In vitro models of the blood-brain barrier are therefore important …

Innovations in studying in vivo cell behavior and pharmacology in complex tissues–microvascular endothelial cells in the spotlight

E Langenkamp, JAAM Kamps, M Mrug… - Cell and tissue …, 2013 - Springer
Many studies on the molecular control underlying normal cell behavior and cellular
responses to disease stimuli and pharmacological intervention are conducted in single-cell …

Altered expression of genes encoding neurotransmitter receptors in GnRH neurons of proestrous mice

C Vastagh, A Rodolosse, N Solymosi… - Frontiers in cellular …, 2016 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) neurons play a key role in the central regulation
of reproduction. In proestrous female mice, estradiol triggers the pre-ovulatory GnRH surge …

Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate …

N Murugesan, D Paul, Y Lemire, B Shrestha… - Fluids and Barriers of …, 2012 - Springer
Background There is increasing awareness that, aside from producing cerebrospinal fluid,
the choroid plexus (CP) might be a key regulator of immune activity in the central nervous …

Atrioventricular node dysfunction and ion channel transcriptome in pulmonary hypertension

IP Temple, SJRJ Logantha, M Absi… - Circulation …, 2016 - Am Heart Assoc
Background—Heart block is associated with pulmonary hypertension, and the aim of the
study was to test the hypothesis that the heart block is the result of a change in the ion …

Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

S Ge, X Jiang, D Paul, L Song, X Wang… - Fluids and Barriers of the …, 2019 - Springer
Background Immune cell trafficking into the CNS is considered to contribute to pathogenesis
in MS and its animal model, EAE. Disruption of the blood–brain barrier (BBB) is a hallmark of …

Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

E Baldelli, M Mandarano, G Bellezza, EF Petricoin… - Cell Reports …, 2022 - cell.com
Clonal evolution and lineage plasticity are key contributors to tumor heterogeneity and
response to treatment in cancer. However, capturing signal transduction events in coexisting …

Integrated RNA extraction and RT-PCR for semi-quantitative gene expression studies on a microfluidic device

KJ Shaw, EM Hughes, CE Dyer, J Greenman… - Laboratory …, 2013 - nature.com
This paper describes the development of a microfluidic methodology, using RNA extraction
and reverse transcription PCR, for investigating expression levels of cytochrome P450 …