Bone-related diseases are major contributors to morbidity and mortality in elderly people
and the current treatments result in insufficient healing and several complications. One of the …

Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

Injectable hydrogels can fill irregular defects and promote in situ tissue regrowth and
regeneration. The ability of directing stem cell differentiation in a three-dimensional …

Abstract Globally, more than 1.5 million patients undergo bone graft surgeries annually, and
the development of biomaterial scaffolds that mimic natural bone for bone grafting remains a …

With population aging and increased life expectancy, an increasing number of people are
facing musculoskeletal health problems that necessitate therapeutic intervention at defect …

RNA interference (RNAi) may be an effective and valuable tool for promoting the growth of
functional tissue, as short interfering RNA (siRNA) and microRNA (miRNA) can block the …

Supramolecular hydrogels have great potential as biomaterials for tissue engineering
applications or vehicles for delivering therapeutic agents. Herein, a self-healing and pro …

An aging population leads to increasing demand for sustained quality of life with the aid of
novel implants. Patients expect fast healing and few complications after surgery. Increased …

Biomaterial delivery of bioactive agents and manipulation of stem cell fate are an attractive
approach to promote tissue regeneration. Here, smoothened agonist sterosome is …

Impaired fracture healing is a major clinical problem that can lead to patient disability,
prolonged hospitalization, and significant financial burden. Although the majority of fractures …