A comprehensive view of translesion synthesis in Escherichia coli
S Fujii, RP Fuchs - Microbiology and molecular biology reviews, 2020 - Am Soc Microbiol
The lesion bypass pathway, translesion synthesis (TLS), exists in essentially all organisms
and is considered a pathway for postreplicative gap repair and, at the same time, for lesion …
and is considered a pathway for postreplicative gap repair and, at the same time, for lesion …
Translesion Synthesis across the N2-Ethyl-deoxyguanosine Adduct by Human PrimPol
EO Boldinova, PP Ghodke, S Sudhakar… - ACS Chemical …, 2022 - ACS Publications
Primase-DNA polymerase (PrimPol) is involved in reinitiating DNA synthesis at stalled
replication forks. PrimPol also possesses DNA translesion (TLS) activity and bypasses …
replication forks. PrimPol also possesses DNA translesion (TLS) activity and bypasses …
Influence of DNA lesions on polymerase-mediated DNA replication at single-molecule resolution
Faithful replication of DNA is a critical aspect in maintaining genome integrity. DNA
polymerases are responsible for replicating DNA, and high-fidelity polymerases do this …
polymerases are responsible for replicating DNA, and high-fidelity polymerases do this …
Selective functionalization at N 2-position of guanine in oligonucleotides via reductive amination
Chemo-and site-specific modifications in oligonucleotides have wide applicability as
mechanistic probes in chemical biology. However, methods that label specific sites in …
mechanistic probes in chemical biology. However, methods that label specific sites in …
Toxicology of DNA adducts formed upon human exposure to carcinogens: Insights gained from molecular modeling
KA Wilson, RW Kung, SD Wetmore - Advances in Molecular Toxicology, 2016 - Elsevier
Carcinogens arising from many sources (eg, industrial agents, agricultural contaminants,
environmental pollutants, food products, and medications) are known to attach to DNA to …
environmental pollutants, food products, and medications) are known to attach to DNA to …
Characterization of nine cancer-associated variants in human DNA polymerase κ
NM Antczak, AR Walker, HR Stern… - Chemical research in …, 2018 - ACS Publications
Specialized DNA damage-bypass Y-family DNA polymerases contribute to cancer
prevention by providing cellular tolerance to DNA damage that can lead to mutations and …
prevention by providing cellular tolerance to DNA damage that can lead to mutations and …
Synthesis of N2-Deoxyguanosine Modified DNAs and the Studies on Their Translesion Synthesis by the E. coli DNA Polymerase IV
We report the synthesis of N 2-aryl (benzyl, naphthyl, anthracenyl, and pyrenyl)-
deoxyguanosine (dG) modified phosphoramidite building blocks and the corresponding …
deoxyguanosine (dG) modified phosphoramidite building blocks and the corresponding …
2-Substituted 2′-deoxyinosine 5′-triphosphates as substrates for polymerase synthesis of minor-groove-modified DNA and effects on restriction endonuclease …
J Matyašovský, M Hocek - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Five 2-substituted 2′-deoxyinosine triphosphates (dRITP) were synthesized and tested as
substrates in enzymatic synthesis of minor-groove base-modified DNA. Only 2-methyl and 2 …
substrates in enzymatic synthesis of minor-groove base-modified DNA. Only 2-methyl and 2 …
Efficient chemical synthesis of N2-modified guanosine derivatives: a versatile probes for mRNA labeling
S Annamalai, S Muthian, AR Kore - Nucleosides, Nucleotides & …, 2023 - Taylor & Francis
An efficient method for the synthesis of N2-modified guanosine nucleotides such as N2-
[benzyl-N-(propyl) carbamate]-guanosine-5′-O-monophosphate, N2-[benzyl-N-(propyl) …
[benzyl-N-(propyl) carbamate]-guanosine-5′-O-monophosphate, N2-[benzyl-N-(propyl) …
Protocols for Efficient Chemical Synthesis of N2‐Modified Guanosine Phosphate Derivatives: Versatile Probes for mRNA Labeling
A Senthilvelan, M Shanmugasundaram… - Current …, 2023 - Wiley Online Library
A facile, reliable, and efficient method for the synthesis of N2‐modified guanosine
nucleotides such as N2‐[benzyl‐N‐(propyl) carbamate]‐guanosine‐5′‐O …
nucleotides such as N2‐[benzyl‐N‐(propyl) carbamate]‐guanosine‐5′‐O …