Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
Z Yuan, Y Li, S Zhang, X Wang, H Dou, X Yu, Z Zhang… - Molecular cancer, 2023 - Springer
The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases
S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
[HTML][HTML] Changes in the mammary gland during aging and its links with breast diseases: aged mammary gland and breast diseases
J Lin, S Ye, H Ke, L Lin, X Wu, M Guo… - Acta biochimica et …, 2023 - ncbi.nlm.nih.gov
The functional capacity of organisms declines in the process of aging. In the case of breast
tissue, abnormal mammary gland development can lead to dysfunction in milk secretion, a …
tissue, abnormal mammary gland development can lead to dysfunction in milk secretion, a …
[HTML][HTML] Commensal gut microbiota-derived acetate and propionate enhance heart adaptation in response to cardiac pressure overload in mice
Background: The gut microbiota plays a vital role in maintaining tissue homeostasis and
regulating disease pathophysiology; however, the underlying mechanisms remain to be …
regulating disease pathophysiology; however, the underlying mechanisms remain to be …
Immune system effects on breast cancer
Breast cancer is one of the most common cancers in women, with the ability to metastasize
to secondary organs, which is the main cause of cancer-related deaths. Understanding how …
to secondary organs, which is the main cause of cancer-related deaths. Understanding how …
Unsupervised analysis based on DCE-MRI radiomics features revealed three novel breast cancer subtypes with distinct clinical outcomes and biological …
Simple Summary Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is
an important approach for the diagnosis and evaluation of breast cancer (BC) in clinical …
an important approach for the diagnosis and evaluation of breast cancer (BC) in clinical …
The extracellular matrix and vesicles modulate the breast tumor microenvironment
Emerging evidence has shown multiple roles of the tumor microenvironment (TME)
components, specifically the extracellular matrix (ECM), in breast cancer development …
components, specifically the extracellular matrix (ECM), in breast cancer development …
Human breast tissue engineering in health and disease
MB Buchholz, DI Scheerman, R Levato… - EMBO Molecular …, 2024 - embopress.org
The human mammary gland represents a highly organized and dynamic tissue, uniquely
characterized by postnatal developmental cycles. During pregnancy and lactation, it …
characterized by postnatal developmental cycles. During pregnancy and lactation, it …
Features of breast cancer in patients of young age: search for diagnosis optimization and personalized treatment
V Chekhun, О Martynyuk, Y Lukianova… - Experimental …, 2023 - exp-oncology.com.ua
The statistical data of the recent decades demonstrate a rapid growth of breast cancer (BCa)
incidence and a tendency toward its increase especially in young women. In the structure of …
incidence and a tendency toward its increase especially in young women. In the structure of …
Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype
Obesity has been linked with numerous health issues as well as an increased risk of breast
cancer. Although effects of direct obesity in patient outcomes is widely studied, effects of …
cancer. Although effects of direct obesity in patient outcomes is widely studied, effects of …