Updated management of acute severe ulcerative colitis: From steroids to novel medical strategies
L Calméjane, D Laharie, J Kirchgesner… - United European …, 2023 - Wiley Online Library
Acute severe ulcerative colitis (ASUC) occurs in up to 25% of patients with ulcerative colitis
(UC). Therapeutic approaches have evolved during the past years with the increasing bio …
(UC). Therapeutic approaches have evolved during the past years with the increasing bio …
Tofacitinib for biologic-experienced hospitalized patients with acute severe ulcerative colitis: a retrospective case-control study
JA Berinstein, JL Sheehan, M Dias… - Clinical …, 2021 - Elsevier
Background & Aims Despite rescue therapy, more than 30% of patients with acute severe
ulcerative colitis (ASUC) require colectomy. Tofacitinib is a rapidly acting Janus kinase …
ulcerative colitis (ASUC) require colectomy. Tofacitinib is a rapidly acting Janus kinase …
Factors associated with response to rescue therapy in acute severe ulcerative colitis
CFD Li Wai Suen, D Seah, MC Choy… - Inflammatory Bowel …, 2024 - academic.oup.com
Background Acute severe ulcerative colitis (ASUC) is a medical emergency for which
colectomy is required in patients who do not respond to rescue therapy. While previous …
colectomy is required in patients who do not respond to rescue therapy. While previous …
Tofacitinib salvage therapy for children hospitalized for corticosteroid-and biologic-refractory ulcerative colitis
BD Constant, R Baldassano, J Kirsch… - Journal of Pediatric …, 2022 - journals.lww.com
Objectives: Colectomy rates following acute severe ulcerative colitis have plateaued around
20% despite intravenous corticosteroid and intensified anti-tumor necrosis factor (TNF) …
20% despite intravenous corticosteroid and intensified anti-tumor necrosis factor (TNF) …
Therapeutic drug monitoring of infliximab in acute severe ulcerative colitis
BL Gordon, R Battat - Journal of Clinical Medicine, 2023 - mdpi.com
Therapeutic drug monitoring (TDM) is a useful strategy in ulcerative colitis (UC). Nearly a
quarter of UC patients will experience acute severe UC (ASUC) in their lifetime, including …
quarter of UC patients will experience acute severe UC (ASUC) in their lifetime, including …
Rescue Therapies for Steroid-refractory Acute Severe Ulcerative Colitis: A Systematic Review and Network Meta-analysis
CW Huang, HH Yen, YY Chen - Journal of Crohn's and Colitis, 2024 - academic.oup.com
Abstract Background and Aims Approximately 40% of patients with steroid-refractory acute
severe ulcerative colitis [SR ASUC] require colectomies. Advanced therapies may reduce …
severe ulcerative colitis [SR ASUC] require colectomies. Advanced therapies may reduce …
Management of acute severe ulcerative colitis—an update for generalist and specialist clinicians
AJ Kuriakose Kuzhiyanjal, JK Limdi - British Medical Bulletin, 2024 - academic.oup.com
Background Acute severe ulcerative colitis (ASUC) is a potentially life-threatening medical
emergency that occurs in up to 25% of patients with ulcerative colitis. Although intravenous …
emergency that occurs in up to 25% of patients with ulcerative colitis. Although intravenous …
Successful initial tofacitinib treatment for acute severe ulcerative colitis with steroid resistance: a case series
Y Komeda, M Kono, H Kashida… - Annals of …, 2022 - pmc.ncbi.nlm.nih.gov
Background The standard therapy for acute severe ulcerative colitis (ASUC) is intravenous
corticosteroids; however, 30% of ulcerative colitis (UC) patients do not recover with …
corticosteroids; however, 30% of ulcerative colitis (UC) patients do not recover with …
Prevalence and risk factors for early medical and surgical complications following an admission for acute severe ulcerative colitis
A Li, M Coote, L Thin - Therapeutic Advances in …, 2023 - journals.sagepub.com
Background: Risk factors for colectomy following an episode of acute severe ulcerative
colitis (ASUC) have been well studied, but data examining the early complications following …
colitis (ASUC) have been well studied, but data examining the early complications following …
Dose-intensified infliximab rescue therapy for severe ulcerative colitis does not reduce short-term colectomy rates or increase postoperative complications
RS Kosaraju, DJ Wong, EM Roth… - Diseases of the Colon …, 2022 - journals.lww.com
BACKGROUND: Dose-intensified rescue therapy with infliximab for hospitalized patients
with ulcerative colitis has become increasingly popular in recent years. However, there is …
with ulcerative colitis has become increasingly popular in recent years. However, there is …