Recent development and application of membrane chromatography

J Chen, B Yu, H Cong, Y Shen - Analytical and bioanalytical chemistry, 2023 - Springer
Membrane chromatography is mainly used for the separation and purification of proteins
and biological macromolecules in the downstream processing process, also applications in …

Towards next generation high throughput ion exchange membranes for downstream bioprocessing: A review

X Yang, A Merenda, ALA Riyadh, LF Dumée… - Journal of Membrane …, 2022 - Elsevier
Membrane chromatography is recognised as a potential solution to streamline downstream
processing for protein purification, where ion exchange membrane chromatography (IEMC) …

A z2 laterally-fed membrane chromatography device for fast high-resolution purification of biopharmaceuticals

R Ghosh, G Chen, R Roshankhah, U Umatheva… - … of Chromatography A, 2020 - Elsevier
We examine the use of az 2 flow distribution and collection feature for enhancing the
separation efficiency of a laterally-fed membrane chromatography (or LFMC) device. The …

Ultrahigh‐speed, ultrahigh‐resolution preparative separation of protein biopharmaceuticals using membrane chromatography

R Ghosh - Journal of Separation Science, 2022 - Wiley Online Library
This paper discusses ultrahigh‐speed, ultrahigh‐resolution preparative protein separation
using an in‐house designed membrane chromatography device. The performance of the …

Optimization of fluid flow in membrane chromatography devices using computational fluid dynamic simulations

R Roshankhah, R Pelton, R Ghosh - Journal of Chromatography A, 2023 - Elsevier
Flow uniformity within the device is critically important in membrane chromatography.
Recent studies have shown that the design of the device has a significant impact on flow …

Fiber chromatographic enabled process intensification increases monoclonal antibody product yield

SM Anderson, E Seto, D Chau, B Lee… - Biotechnology and …, 2024 - Wiley Online Library
The most straightforward method to increase monoclonal antibody (mAb) product yield is to
complete the purification process in less steps. Here, three different fiber chromatographic …

ALTERNATIVAS CROMATOGRÁFICAS PARA LA REMOCIÓN DE ENDOTOXINAS RESIDUALES EN EL PROCESO DE PURIFICACIÓN DE INMUNOGLOBULINAS …

H Borrero Larger, L Sánchez Gallardo - Revista CENIC Ciencias …, 2023 - scielo.sld.cu
Se evaluaron, dos alternativas cromatográficas de intercambio iónico en modo negativo, a
escala de laboratorio, para la remoción de endotoxinas en soluciones de inmunoglobulina …